97399-91-2
Chemical Structure
Aristolactam A IIIa
Synonym(s): Aristololactam A IIIa; Sch 546909
- CAS No.: 97399-91-2
- Formula:C16H11NO4
- Molecular Weight:281.26
IUPAC Name: 2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-one
InChIKey: PFXGXKFPTAJYHV-UHFFFAOYSA-N
SMILES: O=C1NC2=C3C1=CC(O)=C(OC)C3=C4C(C=CC(O)=C4)=C2
Biological Activity: Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells[1].
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Aristolactam A IIIa | Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells. | |||||||||||||||||||||
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Keywords