99103-16-9
99103-16-9
Chemical Structure
U 66985
- CAS No.: 99103-16-9
- Formula:C32H66NO7P
- Molecular Weight:607.85
IUPAC Name: (R)-2-acetoxy-3-(octadecyloxy)propyl (6-(trimethylammonio)hexyl) phosphate
InChIKey: BHJZCBICHQXZMV-JGCGQSQUSA-N
SMILES: [C@H](COP(OCCCCCC[N+](C)(C)C)(=O)[O-])(COCCCCCCCCCCCCCCCCCC)OC(C)=O
Biological Activity: U 66985 is a platelet-activating factor (PAF) receptor antagonist. U 66985 binds to the PAF receptor site, thereby inhibiting PAF-induced platelet aggregation. U 66985 can be used in studies on the PAF signaling pathway and the functions of lipid inflammatory mediators[1][2][3].
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U 66985 | U 66985 is a platelet-activating factor (PAF) receptor antagonist. U 66985 binds to the PAF receptor site, thereby inhibiting PAF-induced platelet aggregation. U 66985 can be used in studies on the PAF signaling pathway and the functions of lipid inflammatory mediators. | |||||||||||||||||||||
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References
- [1]. Cooney SJ, et al. Combining site specificities of rabbit antibodies to platelet-activating factor (PAF). Molecular immunology. 1990 May;27(5):405-12.
- [2]. Buxton DB, et al. Glycogenolytic and haemodynamic responses to heat-aggregated immunoglobulin G and prostaglandin E2 in the perfused rat liver. The Biochemical journal. 1987 Apr 15;243(2):493-8.
- [3]. Hill CE, et al. Location of platelet activating factor binding in rat liver. The Biochemical journal. 1988 Aug 01;253(3):651-7.
