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UMSCC22B

Definition:

UMSCC22B is a human cancer cell line derived from Cervical lymph node and associated with Hypopharyngeal squamous cell carcinoma and Squamous cell carcinoma of the hypopharynx. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. UMSCC22B is used as an in vitro model of Hypopharyngeal squamous cell carcinoma and Squamous cell carcinoma of the hypopharynx to investigate tumor-cell growth, cell survival, and pharmacological response.

Verweise:

[1]. Koldovsky P, et al. Immunohistochemical examination of 11 cell lines derived from human head and neck squamous cell carcinomas, their recurrences or metastases. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 1995;252(6):359-65.

[2]. Alley MC, et al. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer research. 1988;48(3):589-601.

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