Biotin-PEG3-OH
Based on 1 Customer Validation
Biotin-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit : 98.14%
- CAS. Nr.: 1263044-40-1
- Formel: C16H29N3O5S
- Molecular Weight:375.48
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 1263044-40-1
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Appearance Solid
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Molecular Weight 375.48
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Formel C16H29N3O5S
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Color White to off-white
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SMILES
O=C(NCCOCCOCCO)CCCCC1SCC(C1N2)NC2=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 250 mg/mL (665.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6633 mL | 13.3163 mL | 26.6326 mL | 66.5814 mL |
| 5 mM | 0.5327 mL | 2.6633 mL | 5.3265 mL | 13.3163 mL | |
| 10 mM | 0.2663 mL | 1.3316 mL | 2.6633 mL | 6.6581 mL | |
| 15 mM | 0.1776 mL | 0.8878 mL | 1.7755 mL | 4.4388 mL | |
| 20 mM | 0.1332 mL | 0.6658 mL | 1.3316 mL | 3.3291 mL | |
| 25 mM | 0.1065 mL | 0.5327 mL | 1.0653 mL | 2.6633 mL | |
| 30 mM | 0.0888 mL | 0.4439 mL | 0.8878 mL | 2.2194 mL | |
| 40 mM | 0.0666 mL | 0.3329 mL | 0.6658 mL | 1.6645 mL | |
| 50 mM | 0.0533 mL | 0.2663 mL | 0.5327 mL | 1.3316 mL | |
| 60 mM | 0.0444 mL | 0.2219 mL | 0.4439 mL | 1.1097 mL | |
| 80 mM | 0.0333 mL | 0.1665 mL | 0.3329 mL | 0.8323 mL | |
| 100 mM | 0.0266 mL | 0.1332 mL | 0.2663 mL | 0.6658 mL |
Biotin-PEG3-OH Related Classifications
HY-135924 Related Classifications
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