1184847-16-2
1184847-16-2
Chemical Structure
JNJ-40413269
- CAS. Nr.: 1184847-16-2
- Formula:C19H15ClF3N3O
- Molecular Weight:393.79
IUPAC Name: (R)-2-((6-(3-chloro-4-(trifluoromethyl)phenyl)pyrimidin-4-yl)amino)-1-phenylethan-1-ol
InChIKey: MDJZLXVNWZQKAO-KRWDZBQOSA-N
SMILES: FC(F)(F)C1=CC=C(C2=NC=NC(NC[C@H](O)C3=CC=CC=C3)=C2)C=C1Cl
Biological Activity: JNJ-40413269 is an inhibitor for FAAH, that inhibits human FAAH and rats FAAH with IC50 of 28 nM and 270 nM. JNJ-40413269 exhibits analgesic efficacy in rat spinal nerve ligation model and exhibits good pharmacokinetic characteristics in rats[1].
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JNJ-40413269 | JNJ-40413269 is an inhibitor for FAAH, that inhibits human FAAH and rats FAAH with IC50 of 28 nM and 270 nM. JNJ-40413269 exhibits analgesic efficacy in rat spinal nerve ligation model and exhibits good pharmacokinetic characteristics in rats. | |||||||||||||||||||||
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