MPV17L - MPV17 mitochondrial inner membrane protein like Gene

Also Known as M-LPH; MLPH1; MLPH2; MPV17L1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 255027

About MPV17L

Cytogenetic location: 16p13.11 Genomic coordinates (GRCh38): 16:15,395,754-15,413,271 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 256 orthologues and 3 paralogues. Broad expression in kidney (RPKM 1.8), duodenum (RPKM 1.5) and 20 other tissues.

Summary

Involved in negative regulation of hydrogen peroxide biosynthetic process; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and Reactive Oxygen Species metabolic process. Located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

MPV17L Products (2)

mRNA Protein Name
NM_001128423.2 NP_001121895.1 mpv17-like protein isoform 1
NM_173803.4 NP_776164.2 mpv17-like protein isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of hydrogen peroxide biosynthetic process IDA
IDA: Inferred from direct assay
22306510 GOA
involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IDA
IDA: Inferred from direct assay
22306510 GOA
involved in reactive oxygen species metabolic process IDA
IDA: Inferred from direct assay
16631601 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in peroxisome IDA
IDA: Inferred from direct assay
16631601 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MPV17L Protein Structure

Mpv17_PMP22

Mpv17_PMP22: Mpv17 / PMP22 family (105 - 168)

  • 0
  • 100
  • 196 a.a.
Protein Preferred Names Protein Names

mpv17-like protein

  • M-LP homolog

Related Diseases

Diseases Alias
Ross River Fever

  • Ross River Virus Disease

  • Ross River Virus Infection
Autosomal Dominant Nonsyndromic Deafness 77

  • Dfna77
Autosomal Dominant Alport Syndrome

  • Alport Syndrome, Autosomal Dominant

  • Alport Syndrome Dominant Type

  • Renal Failure And Sensorineural Hearing Loss

  • Alport Syndrome, Dominant Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08632 MPV17L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MPV17L RGD RGD:2324483
Mus musculus MPV17L MGD MGI:2135951
Others MPV17L NCBI