Glu-AMS TEA
Based on 1 Customer Validation
Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM.
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- CAS. Nr.: 1810728-44-9
- Formel: C21H36N8O9S
- Molecular Weight:576.62
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Speicherung:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1810728-44-9
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Appearance Solid
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Molecular Weight 576.62
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Formel C21H36N8O9S
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SMILES
CCN(CC)CC.O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1COS(NC([C@@H](N)CCC(O)=O)=O)(=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (173.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Sébastien P Blais, et al. tRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications. PLoS One. 2015 Jun 3;10(6):e0130238. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7342 mL | 8.6712 mL | 17.3424 mL | 43.3561 mL |
| 5 mM | 0.3468 mL | 1.7342 mL | 3.4685 mL | 8.6712 mL | |
| 10 mM | 0.1734 mL | 0.8671 mL | 1.7342 mL | 4.3356 mL | |
| 15 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8904 mL | |
| 20 mM | 0.0867 mL | 0.4336 mL | 0.8671 mL | 2.1678 mL | |
| 25 mM | 0.0694 mL | 0.3468 mL | 0.6937 mL | 1.7342 mL | |
| 30 mM | 0.0578 mL | 0.2890 mL | 0.5781 mL | 1.4452 mL | |
| 40 mM | 0.0434 mL | 0.2168 mL | 0.4336 mL | 1.0839 mL | |
| 50 mM | 0.0347 mL | 0.1734 mL | 0.3468 mL | 0.8671 mL | |
| 60 mM | 0.0289 mL | 0.1445 mL | 0.2890 mL | 0.7226 mL | |
| 80 mM | 0.0217 mL | 0.1084 mL | 0.2168 mL | 0.5420 mL | |
| 100 mM | 0.0173 mL | 0.0867 mL | 0.1734 mL | 0.4336 mL |
Glu-AMS TEA Related Classifications
HY-159628A Related Classifications
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