Glu-AMS
Glu-AMS is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM.
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- CAS. Nr.: 859213-87-9
- Formel: C15H21N7O9S
- Molecular Weight:475.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
4.9 μM
Compound: GluSA
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Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction
Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction
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[PMID: 18438987] |
Chemical Information
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CAS. Nr. 859213-87-9
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Molecular Weight 475.43
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Formel C15H21N7O9S
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1COS(NC([C@@H](N)CCC(O)=O)=O)(=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Sébastien P Blais, et al. tRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications. PLoS One. 2015 Jun 3;10(6):e0130238. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Glu-AMS Related Classifications
HY-159628 Related Classifications
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