HKI12134085
HKI12134085 (compound 3) is an orally available antibacterial nitrobenzothiazinone (BTZ) derivative with activity against Mycobacterium tuberculosis. HKI12134085 has in vivo inhibitory potency in a BALB/c mouse model of Mycobacterium tuberculosis infection.
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- CAS. Nr.: 2102393-11-1
- Formel: C18H18F3N3O5S
- Molecular Weight:445.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | CC50 |
>1.1 x 102μM
Compound: 3
|
Cytotoxicity against human HeLa cells assessed as cytolytic effect incubated for 72 hrs by methylene blue staining based colorimetric analysis
Cytotoxicity against human HeLa cells assessed as cytolytic effect incubated for 72 hrs by methylene blue staining based colorimetric analysis
|
[PMID: 38071794] |
Chemical Information
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CAS. Nr. 2102393-11-1
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Molecular Weight 445.41
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Formel C18H18F3N3O5S
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SMILES
[O-][N+](C1=C(SC(N2CCC3(OC[C@H](C)O3)CC2)=NC4=O)C4=C(C)C(C(F)(F)F)=C1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)