MDM2-IN-26
MDM2-IN-26 (compound A3) is an MDM2 inhibitor that can activate the tumor suppressor function of p53 by blocking the interaction between MDM2 and p53 (MDM2 is the main negative regulator of p53). MDM2-IN-26 can be used for cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1818393-11-1
- Formel: C32H32Cl2F3N3O4
- Molecular Weight:650.52
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
MDM2[1].
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| SJSA-1 | IC50 |
0.17 μM
Compound: 57
|
Cytotoxicity against p53 expressing human SJSA1 cells assessed as cell growth inhibition by WST8 assay
Cytotoxicity against p53 expressing human SJSA1 cells assessed as cell growth inhibition by WST8 assay
|
[PMID: 28339198] |
Chemical Information
-
CAS. Nr. 1818393-11-1
-
Molecular Weight 650.52
-
Formel C32H32Cl2F3N3O4
-
SMILES
OC(C12CCC(CC2)(NC([C@H]3[C@H](C4=CC=CC(Cl)=C4F)[C@@]5(C(C=CC(Cl)=C6)=C6NC5=O)C7(CCC(F)(F)CC7)N3)=O)CC1)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MDM2-IN-26 Related Classifications
HY-162247 Related Classifications
Powered by Bioz