MK16
Based on 1 Customer Validation
MK16 is a lipid material that can be used to construct blood-brain barrier penetrable lipid nanoparticles for mRNA delivery. MK16 facilitates blood-brain barrier crossing via γ-secretase-mediated and caveolae-mediated transcytosis. MK16 can be used for drug delivery research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.86%
- Formel: C55H91ClF2N2O7S
- Molecular Weight:997.84
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
Chemical Information
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Appearance Oil
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Molecular Weight 997.84
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Formel C55H91ClF2N2O7S
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Color Colorless to off-white
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SMILES
CC(OCCCCCC)OCCCCCCN(CCCCCCOC(C)OCCCCCC)CCCCCCNC(CC[C@H]1CC[C@@](C2=CC(F)=CC=C2F)(S(C3=CC=C(Cl)C=C3)(=O)=O)CC1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (100.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0022 mL | 5.0108 mL | 10.0216 mL | 25.0541 mL |
| 5 mM | 0.2004 mL | 1.0022 mL | 2.0043 mL | 5.0108 mL | |
| 10 mM | 0.1002 mL | 0.5011 mL | 1.0022 mL | 2.5054 mL | |
| 15 mM | 0.0668 mL | 0.3341 mL | 0.6681 mL | 1.6703 mL | |
| 20 mM | 0.0501 mL | 0.2505 mL | 0.5011 mL | 1.2527 mL | |
| 25 mM | 0.0401 mL | 0.2004 mL | 0.4009 mL | 1.0022 mL | |
| 30 mM | 0.0334 mL | 0.1670 mL | 0.3341 mL | 0.8351 mL | |
| 40 mM | 0.0251 mL | 0.1253 mL | 0.2505 mL | 0.6264 mL | |
| 50 mM | 0.0200 mL | 0.1002 mL | 0.2004 mL | 0.5011 mL | |
| 60 mM | 0.0167 mL | 0.0835 mL | 0.1670 mL | 0.4176 mL | |
| 80 mM | 0.0125 mL | 0.0626 mL | 0.1253 mL | 0.3132 mL | |
| 100 mM | 0.0100 mL | 0.0501 mL | 0.1002 mL | 0.2505 mL |