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Art. -Nr.: HY-111302

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Norgestrienone

Norgestrienone is an orally active 19‑norprogestogen. Norgestrienone is a synthetic steroid that acts as an agonist of the Progesterone Receptor. Norgestrienone can be used in research related to male hormonal contraception.

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CAS. Nr.: 848-21-5
Formel: C₂₀H₂₂O₂
Molecular Weight:294.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

Norgestrienone Chemical Structure

CAS. Nr.: 848-21-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Norgestrienone exhibits a moderate gradual decreasing trend in release rate over 365‑day in‑vitro release from silicone rubber capsules, and the initial steroid loading inside the capsule exerts minimal effect on its release rate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Norgestrienone has an average in‑vivo release rate of 13.2 μg/day/cm from silicone rubber capsules over a one‑year post‑implantation observation period; the calculated expected release rate declines to 11.0 μg/day/cm at the end of the one‑year implantation period^[1].
Norgestrienone (47 mg per silicone rubber capsule; 1-4 capsules) exhibits a dose-dependent contraceptive effect in implant-related studies; implantation of 4 capsules provides contraceptive protection for at least 12-13 months^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 848-21-5
Molecular Weight 294.39
Formel C₂₀H₂₂O₂
SMILES

C#C[C@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3C=C[C@]12C)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. H.A. Nash, et al. Steroid release from Silastic capsules and rods. Contraception. 1978;18 (4):367‑394.

[2]. Coutinho EM. One-year contraception with norgestrienone subdermal silastic implants. Fertil Steril. 1974 Feb;25(2):170-6.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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