848-21-5
Chemical Structure
Norgestrienone
- CAS No.: 848-21-5
- Formula:C20H22O2
- Molecular Weight:294.39
IUPAC Name: (8S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: GVDMJXQHPUYPHP-FYQPLNBISA-N
SMILES: C#C[C@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3C=C[C@]12C)=O
Biological Activity: Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema[1][2].
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Norgestrienone | Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema. | |||||||||||||||||||||
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- [1]. S Diaz, et al. Diaz S, Pavez M, Quinteros E, Diaz J, Robertson DN, Croxatto HB. Clinical trial with subdermal implants containing norgestrienone. Contraception. 1978 Oct;18(4):429-40. [Content Brief]
- [2]. Wu X, et al. Gestrinone combined with ultrasound-guided aspiration and ethanol injection for treatment of chocolate cyst of ovary. J Obstet Gynaecol Res. 2015 May;41(5):712-6. [Content Brief]
Keywords
