Norgestrienone
Norgestrienone is an orally active 19‑norprogestogen. Norgestrienone is a synthetic steroid that acts as an agonist of the Progesterone Receptor. Norgestrienone can be used in research related to male hormonal contraception.
For research use only. We do not sell to patients.
- CAS No.: 848-21-5
- Formula: C20H22O2
- Molecular Weight:294.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Norgestrienone exhibits a moderate gradual decreasing trend in release rate over 365‑day in‑vitro release from silicone rubber capsules, and the initial steroid loading inside the capsule exerts minimal effect on its release rate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Norgestrienone (47 mg per silicone rubber capsule; 1-4 capsules) exhibits a dose-dependent contraceptive effect in implant-related studies; implantation of 4 capsules provides contraceptive protection for at least 12-13 months[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 848-21-5
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Molecular Weight 294.39
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Formula C20H22O2
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SMILES
C#C[C@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3C=C[C@]12C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)