Safrazine
Safrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 33419-68-0
- Formel: C11H16N2O2
- Molecular Weight:208.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Safrazine (0.1-0.5 μM; 0-80 min) strengthenes the inhibitory potency by preincubation in a time-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Safrazine strongly inhibits both 5-HT and PEA deaminations, but shows no selectivity toward the substrate used[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male ddY mice[1]
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Dosage:3, 10, 30 mg/kg
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Administration:Oral
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Result:Inhibited significantly both 5-HT and PEA deaminations at only 3 mg/kg by 77% and 71%, respectively.
Completely reduced both deaminations at 10 and 30 mg/kg and not observed specificity toward substrates.
Chemical Information
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CAS. Nr. 33419-68-0
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Molecular Weight 208.26
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Formel C11H16N2O2
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SMILES
NNC(C)CCC1=CC=C2OCOC2=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Safrazine Related Classifications
HY-148159 Related Classifications
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