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Art. -Nr.: HY-106499

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Sulfinalol

Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity.

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CAS. Nr.: 66264-77-5
Formel: C₂₀H₂₇NO₄S
Molecular Weight:377.50

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Sulfinalol Chemical Structure

CAS. Nr.: 66264-77-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity^[1].

IC₅₀ & Target

β-adrenoceptor

Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen :

In Vivo

Sulfinalol shows direct vasodilator activity and antihypertensive activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)^[1]
Dosage:

0-100 µg
Administration:

Intraarterial injection
Result:

Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs.

Animal Model:

Male spontaneously hypertensive rats (SHR)^[1]
Dosage:

2.5 mg/kg
Administration:

Oral administration
Result:

Reduced pressure of conscious spontaneously hypertensive rats.

Chemical Information

CAS. Nr. 66264-77-5
Molecular Weight 377.50
Formel C₂₀H₂₇NO₄S
SMILES

COC(C=C1)=CC=C1CCC(C)NCC(C2=CC(S(C)=O)=C(O)C=C2)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. E J Sybertz, et al. Studies on the mechanism of the acute antihypertensive and vasodilator actions of several beta-adrenoceptor antagonists. J Cardiovasc Pharmacol. 1982 Sep-Oct;4(5):749-58. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
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- IC₅₀ & Target
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise

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Sulfinalol

Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vivo

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Sulfinalol Related Classifications

HY-106499 Related Classifications

Bioz

Keywords

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