ABL1 - ABL proto-oncogene 1, non-receptor tyrosine kinase Gene

Also Known as ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; BCR-ABL; bcr/abl

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 25

About ABL1

Cytogenetic location: 9q34.12 Genomic coordinates (GRCh38): 9:130,713,043-130,887,675 (from NCBI)

This gene has 3 transcripts (splice variants), 204 orthologues, 32 paralogues and is associated with 141 phenotypes. Ubiquitous expression in endometrium (RPKM 24.7), gall bladder (RPKM 20.6) and 25 other tissues.

Summary

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]

ABL1 Products (2)

mRNA	Protein	Name
NM_007313.3	NP_009297.2	tyrosine-protein kinase ABL1 isoform b
NM_005157.6	NP_005148.2	tyrosine-protein kinase ABL1 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables ATP binding	IDA IDA: Inferred from direct assay	9144171	GOA
enables SH2 domain binding	IPI IPI: Inferred from physical interaction	12384576	GOA
enables SH3 domain binding	IPI IPI: Inferred from physical interaction	7590236	GOA
enables bubble DNA binding	IDA IDA: Inferred from direct assay	9558345	GOA
enables four-way junction DNA binding	IDA IDA: Inferred from direct assay	9558345	GOA
enables kinase activity	IMP IMP: Inferred from mutant phenotype	28288113	GOA
enables magnesium ion binding	IDA IDA: Inferred from direct assay	9144171	GOA
enables manganese ion binding	IDA IDA: Inferred from direct assay	9144171	GOA
enables mitogen-activated protein kinase binding	IPI IPI: Inferred from physical interaction	11121037	GOA
enables neuropilin binding	IPI IPI: Inferred from physical interaction	24863063	GOA
enables non-membrane spanning protein tyrosine kinase activity	IDA IDA: Inferred from direct assay	9461559	GOA
enables non-membrane spanning protein tyrosine kinase activity	IMP IMP: Inferred from mutant phenotype	28428613	GOA
enables phosphotyrosine residue binding	IPI IPI: Inferred from physical interaction	20624904	GOA
enables proline-rich region binding	IDA IDA: Inferred from direct assay	15657060	GOA
enables proline-rich region binding	IPI IPI: Inferred from physical interaction	7590236	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	7590236	GOA
enables protein kinase C binding	IPI IPI: Inferred from physical interaction	10713049	GOA
enables protein kinase activity	IDA IDA: Inferred from direct assay	11120811	GOA
enables protein kinase activity	IMP IMP: Inferred from mutant phenotype	24863063	GOA
enables protein tyrosine kinase activity	EXP EXP: Inferred from Experiment	15657136	GOA
enables protein tyrosine kinase activity	IDA IDA: Inferred from direct assay	7590236	GOA
enables protein tyrosine kinase activity	IMP IMP: Inferred from mutant phenotype	22810897	GOA
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	9558345	GOA
NOT enables supercoiled DNA binding	IDA IDA: Inferred from direct assay	9558345	GOA
enables syntaxin binding	IPI IPI: Inferred from physical interaction	23006999	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in DNA conformation change	IDA IDA: Inferred from direct assay	9558345	GOA
involved in DNA damage response	IDA IDA: Inferred from direct assay	15657060	GOA
involved in activation of protein kinase C activity	IDA IDA: Inferred from direct assay	10713049	GOA
involved in cellular response to hydrogen peroxide	IDA IDA: Inferred from direct assay	10713049	GOA
involved in endothelial cell migration	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in integrin-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in negative regulation of double-strand break repair via homologous recombination	IDA IDA: Inferred from direct assay	9461559	GOA
involved in negative regulation of protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	11121037	GOA
acts upstream of or within negative regulation of ubiquitin-protein transferase activity	IDA IDA: Inferred from direct assay	20823226	GOA
involved in neuropilin signaling pathway	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in peptidyl-tyrosine autophosphorylation	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in peptidyl-tyrosine phosphorylation	IDA IDA: Inferred from direct assay	7590236	GOA
involved in peptidyl-tyrosine phosphorylation	IMP IMP: Inferred from mutant phenotype	24520051	GOA
acts upstream of or within phospholipase C-inhibiting G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	24367707	GOA
involved in platelet-derived growth factor receptor-beta signaling pathway	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in positive regulation of actin filament binding	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	9037071	GOA
acts upstream of or within positive regulation of cytosolic calcium ion concentration	IMP IMP: Inferred from mutant phenotype	24367707	GOA
involved in positive regulation of endothelial cell migration	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in positive regulation of focal adhesion assembly	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in positive regulation of microtubule binding	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in positive regulation of oxidoreductase activity	IDA IDA: Inferred from direct assay	12893824	GOA
involved in positive regulation of peptidyl-tyrosine phosphorylation	IDA IDA: Inferred from direct assay	15657060	GOA
involved in positive regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	24700464	GOA
involved in positive regulation of stress fiber assembly	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in positive regulation of substrate adhesion-dependent cell spreading	IMP IMP: Inferred from mutant phenotype	24863063	GOA
involved in protein autophosphorylation	IDA IDA: Inferred from direct assay	10713049	GOA
involved in protein localization to cytoplasmic microtubule plus-end	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in regulation of Cdc42 protein signal transduction	IMP IMP: Inferred from mutant phenotype	26051942	GOA
involved in regulation of actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in regulation of axon extension	IMP IMP: Inferred from mutant phenotype	24520051	GOA
involved in regulation of microtubule polymerization	IMP IMP: Inferred from mutant phenotype	24520051	GOA
acts upstream of or within response to oxidative stress	IGI IGI: Inferred from genetic interaction	17626041	GOA
involved in signal transduction in response to DNA damage	IDA IDA: Inferred from direct assay	9037071	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	17515907	GOA
located in cytosol	IDA IDA: Inferred from direct assay	11120811	GOA
located in nucleolus	IDA IDA: Inferred from direct assay	12944467	GOA
located in nucleus	IDA IDA: Inferred from direct assay	9168116	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	17888034	GOA
part of protein-containing complex	IPI IPI: Inferred from physical interaction	12384576	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ABL1 Protein Structure

SH3_1

SH2

Pkinase_Tyr

F_actin_bind

0
200
400
600
800
1000
1130 a.a.

Protein Preferred Names	Protein Names
tyrosine-protein kinase ABL1	ABL protooncogene 1 nonreceptor tyrosine kinase Abelson tyrosine-protein kinase 1 BCR-ABL1 p190 BCR/ABL e8a2 fusion BCR/ABL1 e1a2 fusion protein bcr/c-abl oncogene protein c-abl oncogene 1, receptor tyrosine kinase proto-oncogene c-Abl proto-oncogene tyrosine-protein kinase ABL1 v-abl Abelson murine leukemia viral oncogene homolog 1

ABL1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ABL1	P00519	LRRK1	Homo sapiens	Q38SD2	Protein Array	24947832
Intra	ABL1	P00519	TLN2	Homo sapiens	Q9Y4G6	Anti Bait CoIP	19234221
Intra	ABL1	P00519	SORBS3	Homo sapiens	O60504-2	Anti Tag CoIP	16831423
Intra	ABL1	P00519	KIT	Homo sapiens	P10721	FPS	24728074
Intra	ABL1	P00519	PRICKLE3	Homo sapiens	O43900	Peptide Array	17474147
Intra	ABL1	P00519	SLC22A3	Homo sapiens	O75751	Peptide Array	17474147
Intra	ABL1	P00519	MUC1	Homo sapiens	P15941	Anti Bait CoIP	16888623
Intra	ABL1	P00519	ERCC6	Homo sapiens	Q03468	Protein Kinase Assay	17626041
Intra	ABL1	P00519	ERCC6	Homo sapiens	Q03468	Anti Bait CoIP	17626041
Intra	ABL1	P00519	ERCC6	Homo sapiens	Q03468	Confocal	17626041
Intra	ABL1	P00519	EGFR	Homo sapiens	P00533	Ub Reconstruction	31980649
Intra	ABL1	P00519	EGFR	Homo sapiens	P00533	Ub Reconstruction	24658140
Intra	ABL1	P00519	SOS2	Homo sapiens	Q07890	Peptide Array	17474147
Intra	ABL1	P00519	ITGB2	Homo sapiens	P05107	Anti Bait CoIP	19234221
Intra	ABL1	P00519	ITGB2	Homo sapiens	P05107	Pull Down	19234221
Intra	ABL1	P00519	MUC1	Homo sapiens	P15941-12	Pull Down	16888623
Intra	ABL1	P00519	MUC1	Homo sapiens	P15941-12	Anti Bait CoIP	16888623
Intra	ABL1	P00519	MUC1	Homo sapiens	P15941-12	Anti Tag CoIP	16888623
Intra	ABL1	P00519	YWHAZ	Homo sapiens	P63104	Anti Tag CoIP	25852190
Intra	ABL1	P00519	YWHAZ	Homo sapiens	P63104	Anti Tag CoIP	15696159
Intra	ABL1	P00519	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	25852190
Intra	ABL1	P00519	YWHAE	Homo sapiens	P62258	Crosslink	36931259
Intra	ABL1	P00519	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	15696159
Intra	ABL1	P00519	YWHAG	Homo sapiens	P61981	Anti Tag CoIP	25852190
Intra	ABL1	P00519	YWHAG	Homo sapiens	P61981	Crosslink	30021884
Intra	ABL1	P00519	YWHAG	Homo sapiens	P61981	Anti Tag CoIP	15696159
Intra	ABL1	P00519	RIN1	Homo sapiens	Q13671	Anti Bait CoIP	15886098
Intra	ABL1	P00519	RIN1	Homo sapiens	Q13671	Phage Display	37219487
Intra	ABL1	P00519	RIN1	Homo sapiens	Q13671	Protein Kinase Assay	9144171
Intra	ABL1	P00519	TP53	Homo sapiens	P04637	FPS	39009827
Intra	ABL1	P00519	TP53	Homo sapiens	P04637	Phage Display	39009827
Intra	ABL1	P00519	ABI1	Homo sapiens	Q8IZP0	Anti Bait CoIP	18328268
Intra	ABL1	P00519	ABI1	Homo sapiens	Q8IZP0	Pull Down	11418237
Intra	ABL1	P00519	ABI1	Homo sapiens	Q8IZP0	Filter Binding	9593709
Intra	ABL1	P00519	ABI1	Homo sapiens	Q8IZP0	Anti Bait CoIP	17101133
Intra	ABL1	P00519	ABI1	Homo sapiens	Q8IZP0	Anti Tag CoIP	17101133
Intra	ABL1	P00519	ABI1	Homo sapiens	Q8IZP0	SPR	18328268
Intra	ABL1	P00519	NCK1	Homo sapiens	P16333	Peptide Array	17474147
Intra	ABL1	P00519	WASF2	Homo sapiens	Q9Y6W5	Phage Display	37219487
Intra	ABL1	P00519	SORBS1	Homo sapiens	Q9BX66	Pull Down	11374898
Intra	ABL1	P00519	SHB	Homo sapiens	Q15464	Anti Bait CoIP	17112510
Intra	ABL1	P00519	SHB	Homo sapiens	Q15464	Pull Down	17112510
Intra	ABL1	P00519	SFN	Homo sapiens	P31947	Anti Tag CoIP	15696159
Intra	ABL1	P00519	FLNC	Homo sapiens	Q14315	Peptide Array	17474147
Intra	ABL1	P00519	CTNNB1	Homo sapiens	P35222	Protein Kinase Assay	17318191
Intra	ABL1	P00519	ATM	Homo sapiens	Q13315	Anti Bait CoIP	11375976
Intra	ABL1	P00519	AR	Homo sapiens	P10275	FPS	24728074
Intra	ABL1	P00519	MSH5	Homo sapiens	O43196	Y2H	19442657
Intra	ABL1	P00519	MSH5	Homo sapiens	O43196	Anti Tag CoIP	19442657
Intra	ABL1	P00519	MSH5	Homo sapiens	O43196	Anti Bait CoIP	22401567
Intra	ABL1	P00519	SRC	Homo sapiens	P12931	Peptide Array	17474147
Intra	ABL1	P00519	SRC	Homo sapiens	P12931	Anti Bait CoIP	17318191
Intra	ABL1	P00519	VAV1	Homo sapiens	P15498	Pull Down	19234221
Intra	ABL1	P00519	ERBB2	Homo sapiens	P04626	Protein Array	16273093
Intra	ABL1	P00519	CDON	Homo sapiens	Q4KMG0	Anti Tag CoIP	19470755
Intra	ABL1	P00519	ABI2	Homo sapiens	Q9NYB9	Anti Bait CoIP	17101133
Intra	ABL1	P00519	ABI2	Homo sapiens	Q9NYB9	Anti Tag CoIP	17101133
Intra	ABL1	P00519	TOP1	Homo sapiens	P11387	Pull Down	15448168
Intra	ABL1	P00519	CRK	Homo sapiens	P46108	NMR	12384576
Intra	ABL1	P00519	CRK	Homo sapiens	P46108	Peptide Array	17474147
Intra	ABL1	P00519	CRKL	Homo sapiens	P46109	Protein Kinase Assay	22286129
Intra	ABL1	P00519	SNCA	Homo sapiens	P37840	Anti Bait CoIP	27348587
Intra	ABL1	P00519	SNCA	Homo sapiens	P37840	In Gel Kinase Assay	27348587
Intra	ABL1	P00519	SNCA	Homo sapiens	P37840	Anti Tag CoIP	27348587
Intra	ABL1	P00519	MAVS	Homo sapiens	Q7Z434	Far-WB	19914245
Intra	ABL1	P00519	MAVS	Homo sapiens	Q7Z434	Anti Bait CoIP	19914245
Intra	ABL1	P00519	MAVS	Homo sapiens	Q7Z434	Anti Tag CoIP	19914245
Cross	ABL1	P00519	Cdon	Rattus norvegicus	O35158	Y2H	19470755

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ABL1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71685	ABL1 Protein, Human (GST)	P00519-1 (I4-T194)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P77308	ABL1 Protein, Human (Active, sf9, GST)	P00519-2 (P137-S554)	≥ 90%, as determined by reducing SDS-PAGE.

ABL1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P85070	ABL1 Antibody (YA4762)	WB, IHC-P, ICC/IF, FC	Human, Mouse
HY-P86379	ABL1 Antibody (YA6071)	WB, IHC-P, ICC/IF, IP, ELISA	Human

Related Diseases

Diseases	Alias
Myeloid And Lymphoid Neoplasms Associated With Pdgfra Rearrangement	Myeloid/Lymphoid Neoplasm Associated With Pdgfra Rearrangement Myeloid And Lymphoid Neoplasms With Pdgfra Rearrangement
Atypical Chronic Myeloid Leukemia, Bcr-Abl1 Negative	Atypical Chronic Myeloid Leukaemia Atypical Chronic Myeloid Leukemia Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative Acml Atypical Chronic Myeloid Leukaemia Bcr-Abl1 Negative Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative Atypical Cml Subacute Myeloid Leukemia Subacute Myelogenous Leukaemia Subacute Myeloid Leukaemia Subacute Myelosis Atypical Chronic Myeloid Leukaemia, Bcr-Abl-Negative Without Mention Of Remission Subacute Monocytic Leukaemia Without Mention Of Remission Subacute Monocytic Leukaemia
Moyamoya Angiopathy
Bone Marrow Cancer	Malignant Neoplasm Of Bone Marrow Bone Marrow Neoplasm Bone Marrow Tumor Malignant Bone Marrow Tumor Myeloproliferative Disorders Bone Marrow Neoplasms Myeloproliferative Disease Chronic Myeloproliferative Disorder
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Acute Basophilic Leukemia
Hematologic Cancer	Hematologic Neoplasm Hematologic Malignancies Hematologic Neoplasms Blood Cancer Hematologic Malignancy Hematological Tumors Hematopoietic And Lymphoid System Tumor Hematopoietic Cancer Hematopoietic Neoplasm Hematopoietic Tumors Malignant Hematopoietic Neoplasm Liquid Tumor Hematopoietic Neoplasms
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Chronic Myelogenous Leukemia, Bcr-Abl1 Positive	Chronic Myelogenous Leukemia, Bcr/Abl Positive Chronic Myelosis Chronic Myeloid Leukaemia, Bcr-Abl-Positive Without Mention Of Remission
Myeloid Leukemia	Myeloid Leukaemia Leukaemia Myelogenous Leukemia Myelogenous Myeloid Granulocytic Leukaemia Myeloid Granulocytic Leukemia Non-Lymphocytic Leukemia Leukemia, Myeloid Granulocytic Leukaemia Myelogenous Leukaemia Myeloid Leukaemia, Unspecified, Without Mention Of Remission
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Microcephaly	Microencephaly Microcephalus Microcephalic Nanocephaly Congenital Microcephaly Brain Hypoplasia Brain Nondevelopment Cephalic Hypoplasia Undeveloped Cerebrum Undeveloped Brain Micrencephalon Micrencephaly
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
B-Lymphoblastic Leukemia/Lymphoma, Bcr-Abl1-Like	B Lymphoblastic Leukemia/Lymphoma, Bcr-Abl1-Like B-All Bcr-Abl1-Like
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Leukemia, Myeloid, Acute Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Acute Leukemia	Stem Cell Leukaemia Stem Cell Leukemia Acute Leukemias Acute Undifferentiated Leukemia Undifferentiated Leukemia Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission Blast Cell Leukaemia Blast Leukaemia Blastic Leukaemia Undifferentiated Leukaemia
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Precursor T-Cell Acute Lymphoblastic Leukemia	T-All Precursor T-Cell Acute Lymphoblastic Leukemia/Lymphoma Precursor T-Cell Acute Lymphocytic Leukemia Precursor T-Cell Acute Lymphocytic Leukemia/Lymphoma Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Adult T-Cell Lymphoma/Leukemia
Megabladder, Congenital	MGBL Congenital Megabladder
Polycythemia Vera	PV Polycythemia Rubra Vera Prv Osler-Vaquez Disease Chronic Erythremia Polycythaemia Rubra Vera Primary Polycythemia Vaquez Disease Polycythemia Vera, Somatic Osler-Vaquez Syndrome Proliferative Polycythaemia Polycythemia Ruba Vera Acquired Primary Erythrocytosis Heilmeyer-Schoner Disease Vaquez Osler Disease Primary Polycythaemia
Myelodysplastic/Myeloproliferative Neoplasm	Myelodysplastic/Myeloproliferative Disease Myelodysplastic-Myeloproliferative Diseases Myelodysplastic Myeloproliferative Cancer Myelodysplastic Myeloproliferative Disease Myeloproliferative/Myelodysplastic Syndromes
Lip And Oral Cavity Cancer	Oral Cancer Lip And Oral Cavity Carcinoma Malignant Neoplasm Of Mouth
Mantle Cell Lymphoma	Lymphoma, Mantle Cell Lcm Mcl Mantle Zone Lymphoma Lymphoma Mantle-Cell Lymphoma, Mantle-Cell Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse Malignant Lymphoma - Lymphocytic, Intermediate Differentiation Diffuse Small Cleaved-Cell Lymphoma Diffuse Small Cleaved Cell Malignant Lymphoma Small Cleaved Cell Non-Hodgkin Lymphoma Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma Malignant Lymphomatous Polyposis Malignant Small Cell, Noncleaved, Diffuse Lymphoma Malignant Undifferentiated Cell, Non-Burkitt Lymphoma Cleaved Cell Lymphoma Small Cell Mantle Cell Lymphoma Small Cleaved Cell Malignant Lymphoma
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Congenital Anomaly Of Heart Heart Defect Heart Malformation Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Chronic Eosinophilic Leukemia	Pdgfra-Associated Chronic Eosinophilic Leukemia
Polycythemia	Erythrocythemia Polycythemia Vera Polycythaemia Due To High Altitude
Ataxia-Telangiectasia	Ataxia Telangiectasia Louis-Bar Syndrome AT At1 Ataxia-Telangiectasia Syndrome Ataxia - Telangiectasia Variant Boder-Sedgwick Syndrome Louis Bar Syndrome Cerebello-Oculocutaneous Telangiectasia Immunodeficiency With Ataxia Telangiectasia A-T Ataxia Telangiectasia Syndrome Atm Telangiectasia, Cerebello-Oculocutaneous Ataxia-Telangiectasia Variant
Acquired Polycythemia	Secondary Polycythemia Polycythemia, Secondary Secondary Erythrocytosis Polycythemia Secondary
Aggressive Systemic Mastocytosis	Asm Lymphadenopathic Mastocytosis With Eosinophilia
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Chronic Neutrophilic Leukemia	Cnl Leukemia Neutrophilic Chronic
Myeloproliferative Neoplasm	Myeloproliferative Disorder Chronic Myeloproliferative Disease Myeloproliferative Neoplasms Chronic Myeloproliferative Disorder Cmpd Cmpd, U Chronic Myeloproliferative Disorders Mpd Mpn Myeloproliferative Disorders Myeloproliferative Disease Campomelic Dysplasia
Stress Polycythemia	Gaisbock'S Syndrome Polycythemia, Emotional Pseudopolycythaemia Gaisboeck'S Syndrome Pseudopolycythemia Gaisbock Syndrome Stress Erythrocytosis Pseudo-Polycythemia Relative Erythrocytosis
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Hypotrichosis 13	HYPT13 Hypotrichosis With Woolly Hair Hypotrichosis, Type 13
Van Den Ende-Gupta Syndrome	VDEGS Blepharophimosis, Arachnodactyly, And Congenital Contractures Marden-Walker-Like Syndrome Marden-Walker-Like Syndrome Without Psychomotor Retardation Marden Walker Like Syndrome Marden-Walker-Like Syndrome Without Psychmotor Retardation Van Den Ende Gupta Syndrome Marden Walker Like Syndrome Without Psychomotor Retardation Blepharophimosis Arachnodactyly And Congenital Contractures
Acute Biphenotypic Leukemia	Mixed Phenotype Acute Leukemia Acute Leukemia Of Ambiguous Lineage Acute Undifferentiated Leukemia Acute Leukemia Of Indeterminate Lineage Hybrid Acute Leukemia Mixed Lineage Acute Leukemia All With Myeloid Markers Aml With Lymphoid Markers Acute Leukemia Of Undetermined Lineage Bal Biphenotypic Acute Leukemia Undifferentiated Acute Leukemia Mpal Acute Myeloid Leukemia, Minimal Differentiation, Fab M0 Leukemia, Biphenotypic, Acute
B-Lymphoblastic Leukemia/Lymphoma With Iamp21	B-All With Iamp21 Intrachromosomal Amplification Of Chromosome 21
B-Lymphoblastic Leukemia/Lymphoma With Recurrent Genetic Abnormality
B-Lymphoblastic Leukemia/Lymphoma With Bcr-Abl1	B-All With Bcr-Abl1 B-Lymphoblastic Leukemia/Lymphoma With T(9 22)(Q34.1 Q11.2) Bcr-Abl1 B Lymphoblastic Leukemia/Lymphoma With T(9 22)(Q34.1 Q11.2) Bcr-Abl1
Lissencephaly	Pachygyria Broad Gyri Of Cerebrum Large Gyri Of Cerebrum Macrogyria
Leukemia, Acute Lymphoblastic	Acute Lymphoblastic Leukemia ALL Acute Lymphocytic Leukemia Leukemia, Acute Lymphocytic, Susceptibility To, 1 Acute Lymphoblastic Leukaemia Precursor Lymphoblastic Lymphoma/Leukemia Precursor Lymphoid Neoplasm Leukemia, Acute Lymphoblastic, Susceptibility To B-Cell Acute Lymphoblastic Leukemia Leukemia, Acute Lymphocytic 1 Acute Lymphocytic Leukaemia Acute Lymphoblastic Leukemia/Lymphoma All1 Childhood Acute Lymphoblastic Leukemia Leukemia Acute Lymphoblastic 1 Leukemia Acute Lymphoblastic B-Hyperdiploid Leukemia Acute Lymphocytic Leukemia Acute Lymphocytic 1 Leukemia B-Cell Acute Lymphoblastic Leukemia T-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic, 3 ALL3 Lymphoblastic Leukemia Acute Leukemia, Acute, Lymphoblastic Precursor Cell Lymphoblastic Leukemia Lymphoma Leukemia, Lymphocytic, Acute, L1 Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Cataract 36	CTRCT36 Catc4 Autosomal Recessive Congenital Cataract 4 Cataract, Autosomal Recessive Congenital 4 Cataract, Type 36
Lymphoblastic Leukemia, Acute, With Lymphomatous Features	LALL Lymphomatous All Leukemia, Acute Lymphoblastic Acute Lymphoblastic Leukemia With Lymphomatous Features
Pectus Excavatum	Funnel Chest Congenital Pectus Excavatum
Chronic Myelomonocytic Leukemia	Leukemia, Myelomonocytic, Chronic Cmml Leukemia Myelomonocytic Chronic Cmml - [Chronic Myelomonocytic Leukaemia] Chronic Myelomonocytic Leukaemia Without Mention Of Remission Chronic Monocytic Leukaemia Chronic Monocytoid Leukaemia
Leukemia, Chronic Myeloid	Chronic Myeloid Leukemia Chronic Myelogenous Leukemia CML Chronic Granulocytic Leukemia Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib Chronic Myeloid Leukaemia Chronic Granulocytic Leukaemia Chronic Myelogenous Leukaemia Myeloid Leukemia, Chronic Leukemia, Chronic Myelogenous Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic Cml - Chronic Myelogenous Leukemia Cgl Chronic Myelocytic Leukemia Leukemia, Chronic Myeloid, Atypical ACML Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative Myeloid Leukemia Chronic Leukemia, Myeloid, Chronic Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative Cml- [Chronic Myeloid Leukaemia] Cgl - [Chronic Granulocytic Leukaemia] Chronic Myelocytic Leukaemia
B-Cell Adult Acute Lymphocytic Leukemia	Adult B Acute Lymphoblastic Leukemia Adult B Acute Lymphoblastic Leukaemia Adult B-Cell Acute Lymphoblastic Leukaemia Adult B-Cell Acute Lymphoblastic Leukemia Adult B-Cell Lymphocytic Leukaemia Adult B-Cell Lymphocytic Leukemia Adult B-Lymphoblastic Leukaemia Adult B-Lymphoblastic Leukemia B-Cell Adult Acute Lymphocytic Leukaemia B-Cell Adult Acute Lymphoblastic Leukemia
Esophageal Leukoplakia	Leukoplakia Of Esophagus
Chronic Leukemia	Adult Chronic Leukemia Cll Cml
Leiomyomatosis
B-Lymphoblastic Leukemia/Lymphoma	B Lymphoblastic Leukemia/Lymphoma B-All Precursor B Lymphoblastic Lymphoma/Leukemia C-All Lymphoblastic Lymphoma, Nos Common Precursor B All Lymphoblastic B-Cell Lymphoma Pro-B All B-Precursor Lymphoma Lbl - [Lymphoblastic Lymphoma]
Essential Thrombocythemia	Essential Thrombocytosis Familial Thrombocytosis Hemorrhagic Thrombocythemia Hereditary Thrombocythemia Primary Thrombocytosis Idiopathic Thrombocythemia Primary Thrombocythemia Thrombocythemia, Essential Essential Thrombocythaemia Et Familial Thrombocythemia Thrombocythemia Essential
Blood Platelet Disease	Platelet Disorder Blood Platelet Disorders Thrombocytopathy Platelet Dysfunction Platelet Disorders Qualitative Platelet Deficiency
Myelodysplastic Syndrome	Myelodysplastic Syndromes Myelodysplasia MDS Myelodysplastic Syndrome Included Myelodysplastic Syndrome, Susceptibility To, Included Myelodysplastic Syndrome, Somatic Myelodysplastic Syndrome, Susceptibility To
Retinoblastoma	RB Trilateral Retinoblastoma RB1 Retinoblastoma, Trilateral Neuroblastoma Of Retina Rb - Retinoblastoma Eye Cancer, Retinoblastoma Retinal Cancer Retinal Tumor Glioma, Retinal Non-Hereditary Retinoblastoma Childhood Cancer Retinoblastoma Malignant Neoplasm Of Retina Retinal Neoplasms
Wilms Tumor 1	Nephroblastoma Wilms Tumor WT1 Wilms' Tumor Bilateral Wilms Tumor Wilms Tumor, Type 1 Wilms Tumor, Somatic Adult Nephroblastoma Wt1 Disorder Renal Embryonic Tumor Adult Kidney Wilms Tumor Childhood Kidney Wilms Tumor Nonanaplastic Kidney Wilms Tumor
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Hypereosinophilic Syndrome	Eosinophilia HES Eosinophilic Leukocytosis Hypereosinophilic Syndrome, Idiopathic Idiopathic Hypereosinophilic Syndrome Disseminated Eosinophilic Collagen Disease Eosinophilic Disorder Disorders With Increased Eosinophil Counts
Congenital Heart Defects And Skeletal Malformations Syndrome	CHDSKM
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Central Nervous System Leukemia	Leukemia Of The Cns
Myelophthisic Anemia	Myelophthisis Anemia Leukoerythroblastic Anemia, Leukoerythroblastic Leukoerythroblastosis Anemia, Myelophthisic Leukoerythroblastic Anemia
Childhood Leukemia
Testicular Leukemia
Adult Acute Lymphocytic Leukemia	Adult Acute Lymphoid Leukemia Adult All
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Deficiency Anemia	Anemia Deficiency Anemias Anaemia
Juvenile Myelomonocytic Leukemia	Leukemia, Juvenile Myelomonocytic JMML Leukemia, Juvenile Myelomonocytic, Somatic Juvenile Chronic Myelomonocytic Leukemia Juvenile Chronic Myelogenous Leukemia Leukemia, Myelomonocytic, Juvenile Juvenile Myelomonocytic Leukaemia Without Mention Of Remission
Rasopathy	Ras/Mitogen-Activated Protein Kinase Syndrome
Childhood Acute Lymphocytic Leukemia	Childhood Acute Lymphoblastic Leukemia Childhood All Pediatric Acute Lymphoblastic Leukemia Lymphoblastic Leukemia Acute Childhood
Acute Myeloid Leukemia With Bcr-Abl1	Acute Myeleoid Leukemia With Bcr-Abl1
Leukemia	Leukemias Leukaemia, Unspecified, Without Mention Of Remission Aleukemic Leukaemia Chronic Leukaemia Subacute Leukaemia Leukaemia Disorder Leukaemia Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-104010	Asciminib	Inhibitor	99.61%	Yes
HY-104010A	Asciminib hydrochloride	Inhibitor	99.79%	Yes
HY-15728	Radotinib		99.19%	Yes

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13024	Rebastinib		99.84%	Phase 2
HY-137460	Vodobatinib	Inhibitor	98.09%	Phase 2
HY-148794	Risvodetinib	Inhibitor	99.21%	Phase 2
HY-13072	Cenisertib	Inhibitor	99.86%	Phase 1

Pre-clinical Phase

Bioactive Molecules (50)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125845	(S,R,S)-AHPC		99.13%	Unkown
HY-125834	GMB-475		98.69%	Unkown
HY-148061	DB1113		99.86%	Unkown
HY-103032	Multi-kinase inhibitor 1	Inhibitor	99.05%	Unkown
HY-148063	DB0614		99.92%	Unkown
HY-153996	CT1113		99.61%	Unkown
HY-W143698	PDGFRα kinase inhibitor 2	Inhibitor	98.95%	Unkown
HY-145887	BCR-ABL1-IN-1		99.82%	Unkown
HY-148066	DB0662	Degrader	99.66%	Unkown
HY-12338	ON 146040	Inhibitor	95.05%	Unkown
HY-130297	PROTAC BCR-ABL1 ligand 1	Inhibitor	99.17%	Unkown
HY-13072R	Cenisertib (Standard)	Inhibitor	99.87%	Unkown
HY-110402	(S,R,S)-AHPC TFA		/	Unkown
HY-13024A	Rebastinib tosylate		/	Unkown
HY-184100S	Relcobatinib	Inhibitor	/	Unkown
HY-107447S	N-Deshydroxyethyl Dasatinib-d8		/	Unkown
HY-101268	CHMFL-ABL-053	Inhibitor	/	Unkown
HY-101763B	(S,R,S)-AHPC dihydrochloride		/	Unkown
HY-104010S	Asciminib-d4	Inhibitor	/	Unkown
HY-119177	PD173956	Inhibitor	/	Unkown
HY-14979	ML786	Inhibitor	/	Unkown
HY-14979A	ML786 dihydrochloride	Inhibitor	/	Unkown
HY-155112	Antiproliferative agent-30	Inhibitor	/	Unkown
HY-156745	PROTAC DDa-1	Degrader	/	Unkown
HY-15728S	Radotinib-d6		/	Unkown
HY-161445	(S,R,S)-AHPC-Me-piperazine-acetyl-PIP-AcOH		/	Unkown
HY-162489	Tyrosine kinase-IN-8	Inhibitor	/	Unkown
HY-162952	cSRC/BCR-ABL1-IN-1	Inhibitor	/	Unkown
HY-171146	HSN748	Inhibitor	/	Unkown
HY-175281	SJ11646		/	Unkown
HY-179247	BCR-ABL1-IN-2	Inhibitor	/	Unkown
HY-179460	Radotinib dihydrochloride		/	Unkown
HY-181839	DDR1/2 IN-4	Inhibitor	/	Unkown
HY-182792	Embibatinib	Inhibitor	/	Unkown
HY-185227	EphB4-IN-1	Inhibitor	/	Unkown
HY-18819	BCR-ABL-IN-2	Inhibitor	/	Unkown
HY-E70634	ABL1 E255K Recombinant Human Active Protein Kinase		/	Unkown
HY-E70635	ABL1 F317I Recombinant Human Active Protein Kinase		/	Unkown
HY-E70636	ABL1 G250E Recombinant Human Active Protein Kinase		/	Unkown
HY-E70637	ABL1 H396P Recombinant Human Active Protein Kinase		/	Unkown
HY-E70638	ABL1 M351T Recombinant Human Active Protein Kinase		/	Unkown
HY-E70639	ABL1 Q252H Recombinant Human Active Protein Kinase		/	Unkown
HY-E70640	ABL1 T315I Recombinant Human Active Protein Kinase		/	Unkown
HY-E70641	ABL1 Y253F Recombinant Human Active Protein Kinase		/	Unkown
HY-RS00102	ABL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00103	Abl1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00104	ABL1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-13072B	Cenisertib benzoate	Inhibitor	/	Unkown
HY-14142	AP-24226	Inhibitor	/	Unkown
HY-181046	Multi-kinase-IN-14		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ABL1	VGNC	VGNC:69585
Mus musculus	ABL1	MGD	MGI:87859
Bos taurus	ABL1	VGNC	VGNC:50224
Felis catus	ABL1	VGNC	VGNC:68393
Canis familiaris	ABL1	VGNC	VGNC:54912
Rattus norvegicus	ABL1	RGD	RGD:1584969
Others	ABL1	NCBI