BCR-ABL1-IN-2
BCR-ABL1-IN-2 (compound 8) is a potent BCR-ABL1 tyrosine kinase inhibitor. BCR-ABL1-IN-2 exhibits activity in Imatinib (HY-15463) resistant K562/DOX cells with LC50 of 5.29 μM. BCR-ABL1-IN-2 shows no significant toxicity in nontumor cells. BCR-ABL1-IN-2 can be used for chronic myeloid leukemia research.
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- Formule: C35H35N7O
- Masse moléculaire:569.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
BCR-ABL1 |
Chemical Information
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Masse moléculaire 569.70
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Formule C35H35N7O
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SMILES
O=C(C1=CC=C(C=C1)CN2CCC(C3=CC=C(C=C3)N)CC2)NC4=CC=C(C(NC5=NC=CC(C6=CC=CN=C6)=N5)=C4)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)