Cenisertib (Standard)
Based on 1 Customer Validation
Cenisertib (Standard) is the analytical standard of Cenisertib. This product is intended for research and analytical applications. Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. Cenisertib induces major growth-inhibitory effects by blocking the activity of several different molecular targets in neoplastic mast cells (MC). Cenisertib inhibits tumor growth in xenograft models of pancreatic, breast, colon, ovarian, and lung tumors and leukemia.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.87%
- CAS No.: 871357-89-0
- 화학식: C24H30FN7O
- 분자량:451.54
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- 순도&문서
-
Help & FAQs
-
HY-13072
CenisertibMulti-Kinase Inhibitor -
HY-10971
AlisertibAurora A Kinase Inhibitor -
HY-10161
TozasertibAurora A/B/C Inhibitor -
HY-14711
ReversineAutophagy Inducer -
HY-70044
GSK-1070916Aurora B/C Inhibitor -
HY-13520
NocodazoleMicrotubule Inhibitor -
HY-13252
MK-5108Aurora Kinase Inhibitor -
HY-10127
BarasertibAurora B Inhibitor -
HY-12054
HesperadinAurora B Inhibitor -
HY-10128
ZM-447439Aurora A/B Inhibitor -
HY-10126
Barasertib-HQPAAurora B Inhibitor -
HY-10181
DasatinibSrc/Bcr-Abl Inhibitor
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 871357-89-0
-
Appearance Solid
-
분자량 451.54
-
화학식 C24H30FN7O
-
Color White to off-white
-
SMILES
[H][C@@]1([C@H]([C@H]2C(N)=O)NC3=NC(NC4=CC=C(C(C)=C4)N5CCN(CC5)C)=NC=C3F)C[C@]2(C=C1)[H]
-
Synonyms
AS-703569 (Standard); R-763 (Standard)
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Peter B, et al. Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells. Leukemia. 2018 Apr;32(4):1016-1022. [Content Brief]
[2]. McLaughlin J, et al. Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen. J Cancer Res Clin Oncol. 2010 Jan;136(1):99-113. [Content Brief]
[3]. Maryam Shariati, et al. Targeting AKT for cancer therapy. Expert Opin Investig Drugs. 2019 Nov;28(11):977-988. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cenisertib (Standard) Related Classifications
HY-13072R Related Classifications
Powered by Bioz