Crhbp - corticotropin releasing hormone binding protein Gene

Also Known as Crfbp

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29625

Summary

Enables corticotropin-releasing hormone binding activity. Involved in several processes, including cellular response to estrogen stimulus; cellular response to immobilization stress; and cellular response to organic cyclic compound. Located in several cellular components, including axon; cytoplasmic vesicle; and perikaryon. Biomarker of mental depression; obesity; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in mental depression. Orthologous to human CRHBP (corticotropin releasing hormone binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Crhbp Products (1)

mRNA Protein Name
NM_139183.2 NP_631922.1 corticotropin-releasing factor-binding protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables corticotropin-releasing hormone binding IDA
IDA: Inferred from direct assay
1846945 RGD
enables corticotropin-releasing hormone binding IPI
IPI: Inferred from physical interaction
11572971 RGD
enables peptide binding IDA
IDA: Inferred from direct assay
11572971 RGD
enables peptide binding IPI
IPI: Inferred from physical interaction
15223302 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to cocaine IDA
IDA: Inferred from direct assay
14751291 RGD
involved in cellular response to estradiol stimulus IDA
IDA: Inferred from direct assay
15345745 RGD
involved in cellular response to estrogen stimulus IDA
IDA: Inferred from direct assay
15345745 RGD
involved in cellular response to immobilization stress IDA
IDA: Inferred from direct assay
15530648 RGD
involved in hormone metabolic process IEP
IEP: Inferred from expression pattern
15530648 RGD
involved in negative regulation of corticotropin secretion IDA
IDA: Inferred from direct assay
1846945 RGD
involved in synaptic transmission, dopaminergic IEP
IEP: Inferred from expression pattern
18478589 RGD
Cellular Component GO Annotation Evidence References Source
located in axon terminus IDA
IDA: Inferred from direct assay
10524337 RGD
located in dendrite IDA
IDA: Inferred from direct assay
10524337 RGD
located in dense core granule IDA
IDA: Inferred from direct assay
10524337 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
1846945 RGD
located in microtubule IDA
IDA: Inferred from direct assay
10524337 RGD
located in multivesicular body IDA
IDA: Inferred from direct assay
10524337 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
10524337 RGD
located in secondary lysosome IDA
IDA: Inferred from direct assay
10524337 RGD
located in varicosity IDA
IDA: Inferred from direct assay
10524337 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

corticotropin-releasing factor-binding protein

  • CRF-BP

  • CRF-binding protein

  • CRH-BP

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03167 CRHBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19425 Crhbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25916 Crhbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crhbp NCBI NCBI:1393