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Cat. No.: HY-144072

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MRS4620

MRS4620 is a potent CD73 inhibitor, with a K_i of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch.

For research use only. We do not sell to patients.

CAS No.: 2411665-73-9
Formula: C₁₈H₂₄IN₃O₁₁P₂
Molecular Weight:647.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

MRS4620 Chemical Structure

CAS No.: 2411665-73-9

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Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity

Description

MRS4620 is a potent CD73 inhibitor, with a K_i of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch^[1].

Chemical Information

CAS No. 2411665-73-9
Molecular Weight 647.25
Formula C₁₈H₂₄IN₃O₁₁P₂
SMILES

O[C@H]1[C@@](N2C(N(/C(C=C2)=N\OCC3=CC=C(C=C3)I)C)=O)([H])O[C@@H]([C@H]1O)COP(CP(O)(O)=O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scortichini M, et, al. Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors. J Med Chem. 2022 Feb 10;65(3):2409-2433. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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