(+)-Carbovir
(+)-Carbovir (NSC 614846) is an antiviral drug with activity against human immunodeficiency virus type 1. (+)-Carbovir is a nucleoside analog with enhanced chemical and metabolic stability. (+)-Carbovir can be used in AIDS research.
For research use only. We do not sell to patients.
- CAS No.: 124915-24-8
- Formula: C11H13N5O2
- Molecular Weight:247.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | EC50 |
>200 μM
Compound: 45
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The compound was tested in vitro for the anti-HBV activity against 2.2.15 cells
The compound was tested in vitro for the anti-HBV activity against 2.2.15 cells
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[PMID: 10464025] |
Chemical Information
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CAS No. 124915-24-8
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Molecular Weight 247.25
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Formula C11H13N5O2
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SMILES
O=C1NC(N)=NC2=C1N=CN2[C@@H]3C=C[C@@H](C3)CO
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Synonyms
NSC 614846
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(+)-Carbovir Related Classifications
HY-116001 Related Classifications
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