1. Anti-infection
  2. HBV
  3. (-)-Carbovir

(-)-Carbovir is an active compound.

For research use only. We do not sell to patients.

(-)-Carbovir

(-)-Carbovir Chemical Structure

CAS No. : 120443-30-3

Size Price Stock Quantity
100 mg Get quote 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks
1 g Get quote 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks
5 g   Get quote  
10 g   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (-)-Carbovir:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

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Description

(-)-Carbovir is an active compound.

Cellular Effect
Cell Line Type Value Description References
C3H/3T3 CC50
> 20 μM
Compound: 2
Cytostatic concentration required to inhibit C3H/3T3 cell proliferation
Cytostatic concentration required to inhibit C3H/3T3 cell proliferation
[PMID: 15887959]
C3H/3T3 EC50
6 μM
Compound: 2
Effective concentration against murine moloney sarcoma virus in C3H/3T3 cells
Effective concentration against murine moloney sarcoma virus in C3H/3T3 cells
[PMID: 15887959]
CCRF-CEM CC50
160 μM
Compound: 2
Cytostatic concentration required to inhibit CEM cell proliferation
Cytostatic concentration required to inhibit CEM cell proliferation
[PMID: 15887959]
CCRF-CEM CC50
160 μM
Compound: 2
Cytostatic concentration required to inhibit CEM cell proliferation
Cytostatic concentration required to inhibit CEM cell proliferation
[PMID: 15887959]
CCRF-CEM CC50
> 100 μM
Compound: 5, CBV
Cytotoxicity against human CEM cells
Cytotoxicity against human CEM cells
[PMID: 19433343]
CCRF-CEM EC50
2 μM
Compound: 2
Effective concentration against human immunodeficiency virus type 1 in CEM cells
Effective concentration against human immunodeficiency virus type 1 in CEM cells
[PMID: 15887959]
CCRF-CEM EC50
2 μM
Compound: 2
Effective concentration against human immunodeficiency virus type 1 in CEM cells
Effective concentration against human immunodeficiency virus type 1 in CEM cells
[PMID: 15887959]
CCRF-CEM EC50
2.3 μM
Compound: 2
Effective concentration against human immunodeficiency virus type 2 (ROD) in CEM cells
Effective concentration against human immunodeficiency virus type 2 (ROD) in CEM cells
[PMID: 15887959]
CCRF-CEM EC50
2.3 μM
Compound: 2
Effective concentration against human immunodeficiency virus type 2 in CEM cells
Effective concentration against human immunodeficiency virus type 2 in CEM cells
[PMID: 15887959]
HEL CC50
15 μM
Compound: 2
Cytostatic concentration required to inhibit HEL cell proliferation
Cytostatic concentration required to inhibit HEL cell proliferation
[PMID: 15887959]
HepG2 CC50
150 μM
Compound: 2
Cytostatic concentration required to inhibit Hep G2 cell proliferation
Cytostatic concentration required to inhibit Hep G2 cell proliferation
[PMID: 15887959]
HepG2 CC50
150 μM
Compound: 2
Cytostatic concentration required to inhibit Hep G2.2.15 cell proliferation
Cytostatic concentration required to inhibit Hep G2.2.15 cell proliferation
[PMID: 15887959]
HepG2 2.2.15 EC50
10 μM
Compound: 2
Effective concentration againstHBV in Hep G2.2.15 cells
Effective concentration againstHBV in Hep G2.2.15 cells
[PMID: 15887959]
HepG2 2.2.15 EC50
10.5 μM
Compound: 2
Effective concentration against HBV in Hep G2.2.15 cells
Effective concentration against HBV in Hep G2.2.15 cells
[PMID: 15887959]
Huh-7 EC50
> 10 μM
Compound: 5, CBV
Antiviral activity against HCV in human Huh7 cells by RNA replicon assay
Antiviral activity against HCV in human Huh7 cells by RNA replicon assay
[PMID: 19433343]
MT2 EC50
0.19 μg/mL
Compound: 7a (Carbovir)
Effective concentration that increases formazan production in infected MT-2 cells
Effective concentration that increases formazan production in infected MT-2 cells
[PMID: 2296018]
MT2 IC50
41.8 μg/mL
Compound: 7a (Carbovir)
Inhibitory concentration that reduces formazan production in infected MT-2 cells.
Inhibitory concentration that reduces formazan production in infected MT-2 cells.
[PMID: 2296018]
MT4 IC50
4.6 μM
Compound: Carbovir
In vitro effective concentration against HIV-1 in MT-4 cells
In vitro effective concentration against HIV-1 in MT-4 cells
[PMID: 15916425]
P388 ED50
> 100 μg/mL
Compound: 7a (Carbovir)
Inhibitory concentration of compound for P-388 Leukemia cell culture
Inhibitory concentration of compound for P-388 Leukemia cell culture
[PMID: 2296018]
PBL EC50
0.03 μM
Compound: 2
Effective concentration against human immunodeficiency virus type 1 in PBL cells
Effective concentration against human immunodeficiency virus type 1 in PBL cells
[PMID: 15887959]
PBMC CC50
7 μM
Compound: 5, CBV
Cytotoxicity against human PBMC cells
Cytotoxicity against human PBMC cells
[PMID: 19433343]
PBMC EC50
0.2 μM
Compound: Carbovir
Antiviral activity against lamivudine-resistant HIV1 M184V mutant in human PBMC cells by RT assay
Antiviral activity against lamivudine-resistant HIV1 M184V mutant in human PBMC cells by RT assay
[PMID: 17373782]
PBMC EC50
0.55 μM
Compound: Carbovir
In vitro effective concentration against HIV-1 in human peripheral blood mononuclear cells
In vitro effective concentration against HIV-1 in human peripheral blood mononuclear cells
[PMID: 15916425]
Vero CC50
> 100 μM
Compound: 5, CBV
Cytotoxicity against african green monkey Vero cells
Cytotoxicity against african green monkey Vero cells
[PMID: 19433343]
Molecular Weight

247.25

Formula

C11H13N5O2

CAS No.
SMILES

O=C1C2=C(NC(N)=N1)N([C@@H]3C[C@@H](C=C3)CO)C=N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(-)-Carbovir Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(-)-Carbovir
Cat. No.:
HY-116001B
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