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Cat. No.: HY-116001B

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(-)-Carbovir

Name: (-)-Carbovir
Brand: MedChemExpress
SKU: HY-116001B
Price: 260.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (-)-NSC 614846)

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Based on 1 Customer Validation

(-)-Carbovir is an active compound.

For research use only. We do not sell to patients.

Purity: 99.32%
CAS No.: 120443-30-3
Formula: C₁₁H₁₃N₅O₂
Molecular Weight:247.25

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

(-)-Carbovir Chemical Structure

CAS No.: 120443-30-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

(-)-Carbovir is an active compound.

Cellular Effect

Cell Line	Type	Value	Description	References
C3H/3T3	CC₅₀	>20 μM Compound: 2	Cytostatic concentration required to inhibit C3H/3T3 cell proliferation Cytostatic concentration required to inhibit C3H/3T3 cell proliferation	[PMID: 15887959]
C3H/3T3	EC₅₀	6 μM Compound: 2	Effective concentration against murine moloney sarcoma virus in C3H/3T3 cells Effective concentration against murine moloney sarcoma virus in C3H/3T3 cells	[PMID: 15887959]
CCRF-CEM	CC₅₀	>100 μM Compound: 5, CBV	Cytotoxicity against human CEM cells Cytotoxicity against human CEM cells	[PMID: 19433343]
CCRF-CEM	CC₅₀	160 μM Compound: 2	Cytostatic concentration required to inhibit CEM cell proliferation Cytostatic concentration required to inhibit CEM cell proliferation	[PMID: 15887959]
CCRF-CEM	EC₅₀	2 μM Compound: 2	Effective concentration against human immunodeficiency virus type 1 in CEM cells Effective concentration against human immunodeficiency virus type 1 in CEM cells	[PMID: 15887959]
CCRF-CEM	EC₅₀	2.3 μM Compound: 2	Effective concentration against human immunodeficiency virus type 2 (ROD) in CEM cells Effective concentration against human immunodeficiency virus type 2 (ROD) in CEM cells	[PMID: 15887959]
CCRF-CEM	EC₅₀	2.3 μM Compound: 2	Effective concentration against human immunodeficiency virus type 2 in CEM cells Effective concentration against human immunodeficiency virus type 2 in CEM cells	[PMID: 15887959]
HEL	CC₅₀	15 μM Compound: 2	Cytostatic concentration required to inhibit HEL cell proliferation Cytostatic concentration required to inhibit HEL cell proliferation	[PMID: 15887959]
HepG2	CC₅₀	150 μM Compound: 2	Cytostatic concentration required to inhibit Hep G2 cell proliferation Cytostatic concentration required to inhibit Hep G2 cell proliferation	[PMID: 15887959]
HepG2	CC₅₀	150 μM Compound: 2	Cytostatic concentration required to inhibit Hep G2.2.15 cell proliferation Cytostatic concentration required to inhibit Hep G2.2.15 cell proliferation	[PMID: 15887959]
HepG2 2.2.15	EC₅₀	10 μM Compound: 2	Effective concentration againstHBV in Hep G2.2.15 cells Effective concentration againstHBV in Hep G2.2.15 cells	[PMID: 15887959]
HepG2 2.2.15	EC₅₀	10.5 μM Compound: 2	Effective concentration against HBV in Hep G2.2.15 cells Effective concentration against HBV in Hep G2.2.15 cells	[PMID: 15887959]
Huh-7	EC₅₀	>10 μM Compound: 5, CBV	Antiviral activity against HCV in human Huh7 cells by RNA replicon assay Antiviral activity against HCV in human Huh7 cells by RNA replicon assay	[PMID: 19433343]
MT2	EC₅₀	0.19 μg/mL Compound: 7a (Carbovir)	Effective concentration that increases formazan production in infected MT-2 cells Effective concentration that increases formazan production in infected MT-2 cells	[PMID: 2296018]
MT2	IC₅₀	41.8 μg/mL Compound: 7a (Carbovir)	Inhibitory concentration that reduces formazan production in infected MT-2 cells. Inhibitory concentration that reduces formazan production in infected MT-2 cells.	[PMID: 2296018]
MT4	IC₅₀	4.6 μM Compound: Carbovir	In vitro effective concentration against HIV-1 in MT-4 cells In vitro effective concentration against HIV-1 in MT-4 cells	[PMID: 15916425]
P388	ED₅₀	>100 μg/mL Compound: 7a (Carbovir)	Inhibitory concentration of compound for P-388 Leukemia cell culture Inhibitory concentration of compound for P-388 Leukemia cell culture	[PMID: 2296018]
PBL	EC₅₀	0.03 μM Compound: 2	Effective concentration against human immunodeficiency virus type 1 in PBL cells Effective concentration against human immunodeficiency virus type 1 in PBL cells	[PMID: 15887959]
PBMC	CC₅₀	7 μM Compound: 5, CBV	Cytotoxicity against human PBMC cells Cytotoxicity against human PBMC cells	[PMID: 19433343]
PBMC	EC₅₀	0.2 μM Compound: Carbovir	Antiviral activity against lamivudine-resistant HIV1 M184V mutant in human PBMC cells by RT assay Antiviral activity against lamivudine-resistant HIV1 M184V mutant in human PBMC cells by RT assay	[PMID: 17373782]
PBMC	EC₅₀	0.55 μM Compound: Carbovir	In vitro effective concentration against HIV-1 in human peripheral blood mononuclear cells In vitro effective concentration against HIV-1 in human peripheral blood mononuclear cells	[PMID: 15916425]
Vero	CC₅₀	>100 μM Compound: 5, CBV	Cytotoxicity against african green monkey Vero cells Cytotoxicity against african green monkey Vero cells	[PMID: 19433343]

Chemical Information

CAS No. 120443-30-3
Appearance Solid
Molecular Weight 247.25
Formula C₁₁H₁₃N₅O₂
SMILES

O=C1C2=C(NC(N)=N1)N([C@@H]3C[C@@H](C=C3)CO)C=N2
Synonyms

(-)-NSC 614846
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chemoenzymatic synthesis of (–)-carbovir utilizing a whole cell catalysed resolution of 2-azabicyclo [2.2. 1] hept-5-en-3-one

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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