scHAP-1
scHAP-1 is a scrambled HAP-1 peptide, and HAP-1 is a synovial homing peptide. After amino acid sequence scrambling, scHAP-1 still specifically binds to human and rabbit fibroblast-like synoviocytes (FLS), while showing extremely weak binding to human umbilical vein endothelial cells, which proves that it remains an effective FLS-targeting ligand. scHAP-1 can be used in studies related to rheumatoid arthritis.
For research use only. We do not sell to patients.
- Formula: C60H90N18O17
- Molecular Weight:1335.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Animal Model:Wistar rats (female; adjuvant-induced arthritis model)[1]
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Dosage:0.5 mg drug/0.5 ml/250 g rat/day
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Administration:i.v.; two consecutive days
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Result:Showed a 9-fold increase in fluorescence signal in arthritic joints compared to unaffected joints in the same animals at 3 hours post-injection.
Chemical Information
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Molecular Weight 1335.47
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Formula C60H90N18O17
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Sequence
Ala-Leu-Ser-Gln-Ala-Phe-Arg-His-Ala-Phe-Thr-Ser
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Sequence Shortening
ALSQAFRHAFTS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
scHAP-1 Related Classifications
HY-P4096B Related Classifications
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