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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
EP4-R
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "EP4-R" in MCE Product Catalog:
Target:
Research Areas:
BAY-1316957 is a potent, selective and orally active prostaglandin E2 receptor subtype 4 (EP4-R) antagonist with an IC50 of 15.3 nM for human EP4-R. BAY-1316957 has excellent agent metabolism and pharmacokinetics properties, and can be used for endometriosis research .
Cat. No.: HY-111539R
CAS No.: 1613264-40-6
Research Areas:
BAY-1316957 (Standard) is the analytical standard of BAY-1316957 (HY-111539). This product is intended for research and analytical applications. BAY-1316957 is a potent, selective and orally active prostaglandin E2 receptor subtype 4 (EP4-R) antagonist with an IC50 of 15.3 nM for human EP4-R. BAY-1316957 has excellent agent metabolism and pharmacoKinetics properties, and can be used for endometriosis research .
Cat. No.: HY-163651
CAS No.: 2502965-92-4
Synonyms: (R)-CR6086
Target:
Research Areas:
(R)-Vorbipiprant ((R)-CR6086) is an orally active antagonist for prostaglandin E2 receptor 4 (EP4) with Ki of 16.6 nM for human EP4. (R)-Vorbipiprant inhibits PGE2 (HY-101952)-induced cAMP production with an IC50 of 22 nM. (R)-Vorbipiprant exhibits immunomodulatory and anti-angiogenic activities, and ameliorates the collagen-induced arthritis in mice .
Cat. No.: HY-189816
CAS No.: 2639645-80-8
Research Areas:
DT-9081 is an orally active and selective EP4 receptor antagonist, IC50 = 2.49 nM. DT-9081 blocks PGE2/EP4R-mediated cAMP signaling, counteracts EP4R-driven immunosuppression, and restores antitumor immunity. DT-9081 combined with anti-PD-1 antibody significantly improves tumor growth inhibition and animal survival in mouse tumor models. DT-9081 can be used in cancer-related research .
Cat. No.: HY-189816A
Research Areas:
DT-9081 hydrochloride is an orally active and selective EP4 receptor antagonist, IC50 = 2.49 nM. DT-9081 hydrochloride blocks PGE2/EP4R-mediated cAMP signaling, counteracts EP4R-driven immunosuppression, and restores antitumor immunity. DT-9081 hydrochloride combined with anti-PD-1 antibody significantly improves tumor growth inhibition and animal survival in mouse tumor models. DT-9081 hydrochloride can be used in cancer-related research .
Cat. No.: HY-RS11378
Target:
Research Areas:
PTGER4 Human Pre-designed siRNA Set A contains three designed siRNAs for PTGER4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
