AS3566987
AS3566987 is a positive allosteric modulator of the skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3566987 promotes acetylcholine signaling via the skeletal muscle-type nicotinic acetylcholine receptor, and receptor activation requires the involvement of acetylcholine. AS3566987 can be used in the research of neuromuscular diseases (including myasthenia gravis and congenital myasthenic syndrome).
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- Formule: C24H16F3N5O5S2
- Masse moléculaire:575.54
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
AS3566987 (10 μM) acts as a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptors in Hu5/KD3 human myotubes, reducing the EC50 of ACh by 10.4-fold without inducing currents in the absence of ACh[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 575.54
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Formule C24H16F3N5O5S2
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SMILES
FC(F)(F)C(N=C(NC(C(N1C)=C(O)C2=C(C=C(O)C=C2)S1(=O)=O)=O)S3)=C3C(C=N4)=CN=C4C5=CC=CC=C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AS3566987 Related Classifications
HY-188046 Related Classifications
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