FABP7 - fatty acid binding protein 7 Gene

Also Known as MRG; BLBP; FABPB; B-FABP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2173

About FABP7

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:122,749,201-122,784,074 (from NCBI)

This gene has 2 transcripts (splice variants), 283 orthologues and 15 paralogues. Biased expression in brain (RPKM 8.9) and skin (RPKM 0.4).

Summary

The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and Other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

FABP7 Products (4)

mRNA Protein Name
NM_001319039.2 NP_001305968.1 fatty acid-binding protein, brain isoform 2
NM_001319041.2 NP_001305970.1 fatty acid-binding protein, brain isoform 3
NM_001319042.2 NP_001305971.1 fatty acid-binding protein, brain isoform 4
NM_001446.5 NP_001437.1 fatty acid-binding protein, brain isoform 1

FABP7 Protein Structure

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (8 - 131)

  • 0
  • 100
  • 132 a.a.
Protein Preferred Names Protein Names

fatty acid-binding protein, brain

  • brain lipid-binding protein

FABP7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
FABP7 O15540 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra
FABP7 O15540 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra
FABP7 O15540 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra
FABP7 O15540 DMWD Homo sapiens G5E9A7
Validated Y2H
32814053
Intra
FABP7 O15540 DMWD Homo sapiens G5E9A7
Y2H Array
32814053
Intra
FABP7 O15540 DMWD Homo sapiens G5E9A7
Y2H Pooling
32814053
Intra
FABP7 O15540 GRN Homo sapiens P28799-2
Validated Y2H
32814053
Intra
FABP7 O15540 GRN Homo sapiens P28799-2
Y2H Array
32814053
Intra
FABP7 O15540 GRN Homo sapiens P28799-2
Y2H Pooling
32814053
Intra
FABP7 O15540 RNF11 Homo sapiens Q9Y3C5
Y2H Array
32814053
Intra
FABP7 O15540 RNF11 Homo sapiens Q9Y3C5
Y2H Pooling
32814053
Intra
FABP7 O15540 RNF11 Homo sapiens Q9Y3C5
Validated Y2H
32814053
Intra
FABP7 O15540 PMP22 Homo sapiens A0A6Q8PF08
Validated Y2H
32814053
Intra
FABP7 O15540 PMP22 Homo sapiens A0A6Q8PF08
Y2H Pooling
32814053
Intra
FABP7 O15540 PMP22 Homo sapiens A0A6Q8PF08
Y2H Array
32814053
Intra
FABP7 O15540 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
FABP7 O15540 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
FABP7 O15540 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
FABP7 O15540 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
FABP7 O15540 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
FABP7 O15540 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FABP7 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P7666 FABP7 Protein, Human (His) O15540-1 (V2-A132) ≥ 95%, as determined by reducing SDS-PAGE.

FABP7 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P86788 BLBP Antibody (YA6481) WB Human

Related Diseases

Diseases Alias
Adult Central Nervous System Primitive Neuroectodermal Neoplasm

  • Adult Cns Pnet

  • Adult Central Nervous System Primitive Neuroectodermal Tumor
High Grade Glioma

  • Malignant Glioma

  • Glial Cell Tumor

  • Glioma, Malignant

  • Malignant Neuroglial Tumor

  • Neuroglial Tumor

  • Glioma

  • Malignant Gliomas
Renal Cell Carcinoma, Nonpapillary

  • Renal Cell Carcinoma

  • RCC

  • Nonpapillary Renal Cell Carcinoma

  • Clear Cell Renal Cell Carcinoma

  • Hypernephroma

  • Adenocarcinoma Of Kidney

  • Renal Carcinoma, Chromophobe, Somatic

  • Clear Cell Carcinoma Of Kidney

  • Clear-Cell Metastatic Renal Cell Carcinoma

  • Clear Cell Renal Carcinoma

  • Renal Cell Carcinoma, Somatic

  • Conventional Renal Cell Carcinoma

  • Conventional Renal Cell Carcinoma

  • Renal Clear Cell Carcinoma

  • Ccrcc

  • Hereditary Clear Cell Renal Cell Carcinoma

  • Carcinoma, Renal Cell

  • Renal Cell Carcinoma, Clear Cell, Somatic

  • Renal Cell Carcinoma, Clear Cell

  • Clear Cell Kidney Carcinoma

  • Clear Cell Rcc

  • Cystic-Multilocular Variant

  • Clear Cell Renal Cell Adenocarcinoma

  • Hereditary Clear Cell Renal Cell Adenocarcinoma

  • Common Renal Cell Carcinoma

  • Crcc

  • Renal Cell Carcinoma Non-Papillary

  • Carcinoma Renal Cell

  • Renal Cell Cancer

  • Carcinoma, Renal Cell, Nonpapillary
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Hirschsprung Disease 1

  • Hirschsprung Disease

  • Aganglionic Megacolon

  • Hscr

  • Hirschsprung'S Disease

  • Congenital Megacolon

  • Congenital Intestinal Aganglionosis

  • Colonic Aganglionosis

  • Hirschsprung Disease, Susceptibility To, 1

  • Hirschsprung Disease, Protection Against

  • HSCR1

  • Mgc

  • Pelvirectal Achalasia

  • Total Intestinal Aganglionosis

  • Megacolon, Aganglionic

  • Macrocolon

  • Hscr 1

  • Hirschsprung Disease Type 1

  • Hirschsprung Disease, Type 1

  • Congenital Dilatation Of Colon

  • Aganglionosis

  • Congenital Aganglionic Megacolon

  • Aganglionosis Of Colon

  • Bowel Aganglionosis

  • Colon Aganglionosis

  • Hirschsprung Megacolon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-145990 FABPs ligand 6 Inhibitor 99.86% Unkown
HY-Q66655 YRDC-IN-1 / Unkown
HY-RS04663 FABP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17908 Fabp7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24377 Fabp7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FABP7 VGNC VGNC:28699
Canis familiaris FABP7 VGNC VGNC:40563
Felis catus FABP7 VGNC VGNC:62037
Macaca mulatta FABP7 VGNC VGNC:104376
Mus musculus FABP7 MGD MGI:101916
Rattus norvegicus FABP7 RGD RGD:69312
Others FABP7 NCBI