ISO-92
ISO-92 in an inhibitor of MIF. ISO-92 selectively inhibits MIF inflammatory activity with an IC50 of 550 nM. ISO-92 inhibits hypoxia-induced proliferation of CCL-210 cell line dose-dependently. ISO-92 significantly reduces the thickness of pulmonary vascular wall in mouse hypoxia models. ISO-92 can be studied in inflammatory and neurological research.
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- CAS No.: 899433-49-9
- Formule: C16H20FNO4
- Masse moléculaire:309.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 899433-49-9
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Masse moléculaire 309.33
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Formule C16H20FNO4
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SMILES
O=C(OCC(C)(C)C)C[C@H]1CC(C2=CC=C(O)C(F)=C2)=NO1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Perveen, S., et al., (2019). MIF inhibition enhances pulmonary angiogenesis and lung development in congenital diaphragmatic hernia. Pediatric research, 85(5), 711-718. [Content Brief]
[2]. Zhang, Y., et al., (2012). Macrophage migration inhibitory factor mediates hypoxia-induced pulmonary hypertension. Molecular medicine (Cambridge, Mass.), 18(1), 215-223. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ISO-92 Related Classifications
HY-123970 Related Classifications
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