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Cat. No.: HY-128060

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PDE5-IN-42

PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC₅₀ of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11.

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CAS No.: 936449-28-4
Formule: C₂₃H₃₁N₇O₃
Masse moléculaire:453.54

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

PDE5-IN-42 Chemical Structure

CAS No.: 936449-28-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC₅₀ of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11^[1].

IC₅₀ & Target

IC50: 0.04 nM (PDE5)^[1]

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

Chemical Information

CAS No. 936449-28-4
Masse moléculaire 453.54
Formule C₂₃H₃₁N₇O₃
SMILES

O=C(C1CCN(C2=NC(NC3=NC=CC(C)=C3)=C(N(CCOCC)N=C4CC)C4=N2)CC1)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tollefson MB, et al. 1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors. Bioorg Med Chem Lett. 2010 May 15;20(10):3120-4. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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PDE5-IN-42

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PDE5-IN-42 Related Classifications

HY-128060 Related Classifications

Bioz

Keywords

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