PSB-1737

PSB-1737 is a human-selective GPR17 agonist with an EC50 for human GPR17 of 270 nM, and its activity on murine GPR17 is relatively weak (EC50 > 10 μM). PSB-1737 shows no significant inhibition at the glycine binding site of NMDA receptors, and has no significant agonistic or antagonistic activity on P2Y receptor subtypes. PSB-1737 can be used in demyelinating diseases (such as multiple sclerosis) or inflammatory-related anemia.

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  • CAS No.: 139896-80-3
  • Formule: C18H15NO5
  • Masse moléculaire:325.32
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    Please store the product under the recommended conditions in the Certificate of Analysis.

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