Sulfinalol
Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity.
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- CAS No.: 66264-77-5
- Formule: C20H27NO4S
- Masse moléculaire:377.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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β-adrenoceptor |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)[1]
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Dosage:0-100 µg
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Administration:Intraarterial injection
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Result:Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs.
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Animal Model:Male spontaneously hypertensive rats (SHR)[1]
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Dosage:2.5 mg/kg
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Administration:Oral administration
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Result:Reduced pressure of conscious spontaneously hypertensive rats.
Chemical Information
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CAS No. 66264-77-5
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Masse moléculaire 377.50
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Formule C20H27NO4S
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SMILES
COC(C=C1)=CC=C1CCC(C)NCC(C2=CC(S(C)=O)=C(O)C=C2)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sulfinalol Related Classifications
HY-106499 Related Classifications
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