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Cat. No.: HY-119707

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TDR 32750

TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED₅₀ value of 0.014 μM.

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CAS No.: 1428183-45-2
Formule: C₂₂H₂₁F₃N₂O₃
Masse moléculaire:418.41

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

TDR 32750 Chemical Structure

CAS No.: 1428183-45-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED₅₀ value of 0.014 μM^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
Huh-7	CC₅₀	>10 μM Compound: GNF-Pf-1753	NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)	[PMID: 18579783]
L6	EC₅₀	15 μM Compound: 8a, TDR32750	Cytotoxicity against rat L6 cells after 72 hrs by Alamar blue assay Cytotoxicity against rat L6 cells after 72 hrs by Alamar blue assay	[PMID: 23517371]

Chemical Information

CAS No. 1428183-45-2
Masse moléculaire 418.41
Formule C₂₂H₂₁F₃N₂O₃
SMILES

O=C(OCC)C(C1=O)=C(N/C1=C/C2=C(N(C(C)=C2)C3=CC=CC=C3C(F)(F)F)C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Dinakaran Murugesan, et al. Structure-activity relationship studies of pyrrolone antimalarial agents. ChemMedChem. 2013 Sep;8(9):1537-44. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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