CRBN ligand-828
CRBN ligand-828 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-828 can be linked to a target protein ligand via a linker to form a PROTAC.
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- Formel: C₁₈H₂₁BN₄O₄
- Molecular Weight:368.19
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 368.19
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Formel C₁₈H₂₁BN₄O₄
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SMILES
O=C1NC(=O)N(CC1)C2=C3C(N=CN=C3)=CC(=C2)B4OC(C)(C)C(C)(C)O4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)