CU7218
CU7218 competitively binds to the phosphopeptide-binding pocket of 14-3-3ε and blocks its interaction with the 9J10 peptide. CU7218 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 34330-04-6
- Formula: C8H6N2O3S2
- Molecular Weight:242.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
CU7218 (0-1 mM; 20 min) inhibits the interaction between the 9J10 phosphopeptide and 14-3-3ε protein in fluorescence polarization (FP) assays, with an IC50 of 111 μM[1].
CU7218 (0-1 mM; 20 min) inhibits the interaction between the 9J10 phosphopeptide and 14-3-3ε protein in MST assays, with an IC50 of 26.5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 34330-04-6
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Molecular Weight 242.27
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Formula C8H6N2O3S2
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SMILES
O=C(C1=C(C)C2=C(NC(NC2=O)=S)S1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CU7218 Related Classifications
HY-W457608 Related Classifications
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