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Art. -Nr.: HY-N16426

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Mycoleptone A

Mycoleptone A is an azafluorenone compound. Mycoleptone A exhibits certain anti-leishmanial activity, with an LD₅₀ of 28.5 μM against L. major. Mycoleptone A shows cytotoxicity against human prostate cancer cell line PC3, with an IC₅₀ of 10.0 μM. Mycoleptone A can be used in research on anti-parasitic and anti-tumor aspects.

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CAS. Nr.: 1532554-02-1
Formel: C₂₃H₂₄O₈
Molecular Weight:428.43

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Mycoleptone A Chemical Structure

CAS. Nr.: 1532554-02-1

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Biologische Aktivität
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- Cellular Effect
Chemical Information
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Biologische Aktivität

Beschreibung

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Cellular Effect

Cell Line	Type	Value	Description	References
HCT-8	IC₅₀	>58 μM Compound: 2, Mycoleptone A	Cytotoxicity against human HCT8 cells by colorimetric method Cytotoxicity against human HCT8 cells by colorimetric method	[PMID: 24387625]
HL-60	IC₅₀	>58 μM Compound: 2, Mycoleptone A	Cytotoxicity against human HL60 cells by colorimetric method Cytotoxicity against human HL60 cells by colorimetric method	[PMID: 24387625]
Lymphocyte	IC₅₀	>58 μM Compound: 2, Mycoleptone A	Cytotoxicity against human lymphocytes by colorimetric method Cytotoxicity against human lymphocytes by colorimetric method	[PMID: 24387625]
MDA-MB-435	IC₅₀	>58 μM Compound: 2, Mycoleptone A	Cytotoxicity against human MDA-MB-435 cells by colorimetric method Cytotoxicity against human MDA-MB-435 cells by colorimetric method	[PMID: 24387625]
PC-3	IC₅₀	10 μM Compound: 2, Mycoleptone A	Cytotoxicity against human PC3 cells by colorimetric method Cytotoxicity against human PC3 cells by colorimetric method	[PMID: 24387625]
SF-295	IC₅₀	>58 μM Compound: 2, Mycoleptone A	Cytotoxicity against human SF295 cells by colorimetric method Cytotoxicity against human SF295 cells by colorimetric method	[PMID: 24387625]

Chemical Information

CAS. Nr. 1532554-02-1
Molecular Weight 428.43
Formel C₂₃H₂₄O₈
SMILES

CC(OC=C1[C@H](O)[C@@]2(C)O)=CC1=C(CC3=C4C=C(OC=C4[C@H](O)[C@](O)(C)C3=O)C)C2=O
Structure Classification
- Others
Initial Source
- Microorganisms
Mycoleptodiscus indicus
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Andrioli WJ, et al. Mycoleptones A-C and polyketides from the endophyte Mycoleptodiscus indicus. J Nat Prod. 2014 Jan 24;77(1):70-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Mycoleptone A

Alle Parasite Isoform-spezifische Produkte anzeigen

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Mycoleptone A Related Classifications

HY-N16426 Related Classifications