EVI2A - ecotropic viral integration site 2A Gene

Also Known as EVDA; EVI2; EVI-2A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2123

About EVI2A

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,316,410-31,321,622 (from NCBI)

This gene has 3 transcripts (splice variants) and 110 orthologues. Broad expression in brain (RPKM 20.1), appendix (RPKM 18.9) and 18 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVI2A Products (2)

mRNA Protein Name
NM_001003927.3 NP_001003927.1 protein EVI2A isoform 1
NM_014210.4 NP_055025.2 protein EVI2A isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EVI2A Protein Structure

EVI2A

EVI2A: Ectropic viral integration site 2A protein (EVI2A) (5 - 231)

  • 0
  • 100
  • 200
  • 236 a.a.
Protein Preferred Names Protein Names

protein EVI2A

  • ecotropic viral integration site 2A protein homolog

EVI2A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EVI2A P22794 RTP2 Homo sapiens Q5QGT7
Validated Y2H
32296183
Intra
EVI2A P22794 PLPP4 Homo sapiens Q5VZY2
Validated Y2H
32296183
Intra
EVI2A P22794 UBIAD1 Homo sapiens Q9Y5Z9
Validated Y2H
32296183
Intra
EVI2A P22794 GOPC Homo sapiens Q9HD26
Anti Tag CoIP
33961781
Intra
EVI2A P22794 PLP2 Homo sapiens Q04941
Validated Y2H
32296183
Intra
EVI2A P22794 ATP6V0C Homo sapiens P27449
Validated Y2H
32296183
Intra
EVI2A P22794 MALL Homo sapiens Q13021
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant EVI2A Proteins

Cat. No. Product Name Accession Purity
HY-P75757 EVI2A Protein, Human (HEK293, Fc) P22794-1/NP_055025.2 (N31-M133) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Chromosome 17q11.2 Deletion Syndrome

  • Nf1 Microdeletion Syndrome

  • 17q11 Microdeletion Syndrome

  • Neurofibromatosis Type 1 Microdeletion Syndrome

  • Van Asperen Syndrome

  • Del(17)(Q11)

  • Monosomy 17q11

  • Chromosome 17q11.2 Deletion Syndrome, 1.4mb
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04574 EVI2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20920 Evi2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27437 Evi2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EVI2A RGD RGD:1593824
Mus musculus EVI2A MGD MGI:95458