Desamino lenalidomide-5-CO
Based on 1 Customer Validation
Desamino lenalidomide-5-CO is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-CO can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2866307-09-5
- Formula: C14H12N2O4
- Molecular Weight:272.26
-
Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
|
Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2866307-09-5
-
Appearance Solid
-
Molecular Weight 272.26
-
Formula C14H12N2O4
-
Color White to light yellow
-
SMILES
O=CC1=CC=C2C(=C1)C(=O)N(C2)C3C(=O)NC(=O)CC3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
-
Data Sheet (241 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)