2. PROTAC
  3. Ligands for E3 Ligase
  4. Desamino lenalidomide-CH2NH2 hydrochloride

Desamino lenalidomide-CH2NH2 hydrochloride 

Cat. No.: HY-W584677 Pureza: ≥95.0%
COA
SDS
Instrucciones de manejo Technical Support

Desamino lenalidomide-CH2NH2 hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-CH2NH2 hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.

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Desamino lenalidomide-CH2NH2 hydrochloride

Desamino lenalidomide-CH2NH2 hydrochloride Estructura química

No. CAS : 2248702-12-5

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Desamino lenalidomide-CH2NH2 hydrochloride Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Ligands for E3 Ligase:

Ver todas las isoformas
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B

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Descripciòn

Desamino lenalidomide-CH2NH2 hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-CH2NH2 hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Desamino lenalidomide-CH2NH2 hydrochloride Related Antibodies
Peso molecular

309.75

Fòrmula

C14H16ClN3O3
No. CAS
Appearance

Solid

Color

Off-white to gray

SMILES

O=C1NC(C(CC1)N2C(C3=CC(CN)=CC=C3C2)=O)=O.Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Pureza y Documentación

Purity: ≥95.0%

SDS (393 KB)

COA (247 KB) HNMR (135 KB)

Instrucciones de manejo (2659 KB)
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Desamino lenalidomide-CH2NH2 hydrochloride Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desamino lenalidomide-CH2NH22248702-12-5Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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Nombre del producto:
Desamino lenalidomide-CH2NH2 hydrochloride
Cat. No.:
HY-W584677
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