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  6. Dextran sulfate sodium salt (MW 35000-45000)

Dextran sulfate sodium salt (MW 35000-45000) 

Cat. No.: HY-116282C
COA Handling Instructions

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Dextran sulfate sodium salt (MW 35000-45000) is a polymer of anhydroglucose with the molecular weight range of 35000-45000. Dextran sulfate sodium salt can be used to induce colitis. Dextran sulfate sodium salt also can inhibit the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells.

For research use only. We do not sell to patients.

Dextran sulfate sodium salt (MW 35000-45000) Chemical Structure

Dextran sulfate sodium salt (MW 35000-45000) Chemical Structure

CAS No. : 9011-18-1

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Based on 2 publication(s) in Google Scholar

Other Forms of Dextran sulfate sodium salt (MW 35000-45000):

Dextran sulfate sodium salt (MW 35000-45000) Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Dextran sulfate sodium salt (MW 35000-45000)

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Description

Dextran sulfate sodium salt (MW 35000-45000) is a polymer of anhydroglucose with the molecular weight range of 35000-45000. Dextran sulfate sodium salt can be used to induce colitis. Dextran sulfate sodium salt also can inhibit the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells[1][2][3].

In Vitro

Dextran sulfate (25 μg/mL) sodium salt completely protects MT-4 cells against HIV-1-induced cytopathogenicity[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dextran sulfate sodium salt (MW 35000-45000) Related Antibodies
In Vivo

Dextran sulfate sodium salt (MW 35000-45000) can be used in animal modeling to construct colitis models.

Dextran sulfate sodium salt (3%; in drinking water for 7 days) induces colitis in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

35000-45000

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Dextran sulfate sodium salt (MW 35000-45000)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5.5 mg/mL (ultrasonic and warming and heat to 60°C)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (Infinity mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

COA (241 KB)

Handling Instructions (2659 KB)
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Dextran sulfate sodium salt (MW 35000-45000) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dextran sulfate sodium salt (MW 35000-45000)9011-18-1ApoptosisHIVHuman immunodeficiency viruscolitishuman immunodeficiency virusInhibitorinhibitorinhibit

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