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Cat. No.: HY-161064

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DHFR-IN-15

DHFR-IN-15 (compound 34) is a dihydrofolate reductase (DHFR) inhibitor with potential anticancer activity. DHFR-IN-15 effectively binds to DHFR in cells, reducing DHFR levels to 10 nM.

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CAS No.: 3049475-31-9
화학식: C₁₈H₁₈N₆O₂
분자량:350.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DHFR-IN-15 Chemical Structure

CAS No.: 3049475-31-9

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

DHFR-IN-15 (compound 34) is a dihydrofolate reductase (DHFR) inhibitor with potential anticancer activity. DHFR-IN-15 effectively binds to DHFR in cells, reducing DHFR levels to 10 nM^[1].

Chemical Information

CAS No. 3049475-31-9
분자량 350.37
화학식 C₁₈H₁₈N₆O₂
SMILES

CN(C1=CC=C(C2=C(N)N=C(N)N=C2)C=C1[N+]([O-])=O)CC3=CC=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Brown JI, et al. Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens. Eur J Med Chem. 2024 Jan 15;264:115971. [Content Brief]

Calculators

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Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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