DHFR-IN-17
DHFR-IN-17 (compound j9) is an oral active SaDHFR inhibitor with the IC50 of 0.97 nM. DHFR-IN-17 shows antibacterial activity against S. aureus with the minimum inhibitory concentration of 0.031 μg/mL.
For research use only. We do not sell to patients.
- Formula: C17H21IN4O2
- Molecular Weight:440.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:MRSA-induced epidermal infections in C57 mice[1]
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Dosage:2、5 and 10mg/kg
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Administration:Oral gavagefor 3 consecutive days
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Result:Alleviates the skin infection damage.
Chemical Information
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Molecular Weight 440.28
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Formula C17H21IN4O2
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SMILES
CC(C1=C(C=C(C(OCC2CC2)=C1)I)OC3=CN=C(N=C3N)N)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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