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Cat. No.: HY-W006672

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Dibenzo[b,e]oxepin-11(6H)-one

Name: Dibenzo[b,e]oxepin-11(6H)-one
Brand: MedChemExpress
SKU: HY-W006672
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Dibenzo[b,e]oxepin-11(6H)-one (Compound 1a) is a dibenzoxepinone derivative that exhibits significant antiparasitic activity.

For research use only. We do not sell to patients.

CAS No.: 4504-87-4
Formula: C₁₄H₁₀O₂
Molecular Weight:210.23

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Dibenzo[b,e]oxepin-11(6H)-one Chemical Structure

CAS No.: 4504-87-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

Dibenzo[b,e]oxepin-11(6H)-one (Compound 1a) is a dibenzoxepinone derivative that exhibits significant antiparasitic activity^[1].

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In Vitro

Dibenzo[b,e]oxepin-11(6H)-one (Compound 1a) exhibits inhibitory effects on the motility of the nematode Caenorhabditis elegans, with an IC₅₀ value of 389 μM. Treatment with a concentration of 1 mM for 10 minutes can reduce the worm's thrashes by 80%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 4504-87-4
Appearance Solid
Molecular Weight 210.23
Formula C₁₄H₁₀O₂
Color Off-white to light yellow
SMILES

O=C1C2=CC=CC=C2COC3=CC=CC=C31
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (479 KB)
- English - EN (479 KB)
- Français - FR (479 KB)
- Deutsch - DE (479 KB)
- Norwegian - NO (479 KB)
- Español - ES (479 KB)
- Swedish - SV (479 KB)
- Italian - IT (479 KB)
- Korean - KR (479 KB)
- Portuguese - PT (479 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scoccia J, et al. Iron (II) promoted direct synthesis of dibenzo [b, e] oxepin-11 (6H)-one derivatives with biological activity. A short synthesis of doxepin[J]. Tetrahedron, 2017, 73(20): 2913-2922.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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Dibenzo[b,e]oxepin-11(6H)-one

All Parasite Isoforms