(S)-HTS-3
(S)-HTS-3 is a Lysophosphatidylcholine acyltransferase 3 (LPCAT3/MBOAT5) inhibitor with a human IC50 of 4.1 μM. (S)-HTS-3 inhibits the acyltransferase activity of LPCAT3. (S)-HTS-3 modestly reduces incorporation of deuterated arachidonic acid into C20:4 phosphatidylserine in myeloid leukemia cells.
For research use only. We do not sell to patients.
- CAS No.: 2771208-82-1
- Formula: C17H18F2N2O
- Molecular Weight:304.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
(S)-HTS-3 weakly inhibits recombinant human LPCAT3 in membrane lysates from HEK293T cells with an IC50 of 4.1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2771208-82-1
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Molecular Weight 304.33
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Formula C17H18F2N2O
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SMILES
O=C(C1=CC(F)=CC(F)=C1)NC[C@H](C2=CC=CC=C2)N(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-HTS-3 Related Classifications
HY-158790A Related Classifications
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