Zalypsis
Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks.
For research use only. We do not sell to patients.
- CAS No.: 308359-57-1
- Formula: C37H38F3N3O8
- Molecular Weight:709.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 308359-57-1
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Molecular Weight 709.71
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Formula C37H38F3N3O8
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SMILES
O=C(NC[C@H]1C2=C3C(OCO3)=C(C)C(OC(C)=O)=C2C[C@]4([H])N1[C@@H](O)[C@@]5([H])N(C)[C@]4([H])C6=C(C5)C=C(C)C(OC)=C6O)/C=C/C7=CC(C(F)(F)F)=CC=C7
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Synonyms
PM00104
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Duan Z, et al. Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines. Cancer Chemother Pharmacol. 2009 May;63(6):1121-9. [Content Brief]
[2]. Petek BJ, et al. PM00104 (Zalypsis®): a marine derived alkylating agent. Molecules. 2014 Aug 15;19(8):12328-35. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zalypsis Related Classifications
HY-16401 Related Classifications
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