2. PROTAC
  3. Ligands for E3 Ligase
  4. E3 ligase Ligand 35

E3 ligase Ligand 35 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-27 (HY-168229).

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E3 ligase Ligand 35

E3 ligase Ligand 35 Estructura química

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E3 ligase Ligand 35 Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B

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Descripciòn

E3 ligase Ligand 35 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-27 (HY-168229)[1].

IC50 & Target

VHL

 

Peso molecular

444.46

Fòrmula

C22H25FN4O5
SMILES

OC1=NOC([C@H](C(N2C[C@H](O)C[C@H]2C(N[C@H](C3=CC(F)=C(C#N)C=C3)C)=O)=O)C(C)C)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
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Referencias
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E3 ligase Ligand 35 Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E3 ligase Ligand 35Ligands for E3 LigaseE3 ligase-recruiting MoietyPROTACsInhibitorinhibitorinhibit

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Nombre del producto:
E3 ligase Ligand 35
Cat. No.:
HY-168232
Cantidad:
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