1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Erythrodiol

Erythrodiol 

Cat. No.: HY-N2419
Handling Instructions

Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis.

For research use only. We do not sell to patients.

Erythrodiol Chemical Structure

Erythrodiol Chemical Structure

CAS No. : 545-48-2

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Description

Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1].

IC50 & Target

ABCA1 protein[1]

In Vitro

Erythrodiol (1-15 μM; 24 hours) enhances ABCA1 protein level in a concentration-dependent manner, and reachs significance at 10 and 15 μM[1].

Western Blot Analysis[1]

Cell Line: THP-1 macrophage cells
Concentration: 1 μM, 2.5 μM, 5 μM, 10 μM, and 15 μM
Incubation Time: 24 hours
Result: Increased ABCA1 protein expression.
Molecular Weight

442.72

Formula

C₃₀H₅₀O₂

CAS No.

545-48-2

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Erythrodiol
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HY-N2419
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