Four new triterpenoids from Maytenus ilicifolia

  • J Nat Prod. 2004 Mar;67(3):469-71. doi: 10.1021/np030379d.
Ayumi Ohsaki  1 ,  Yoji Imai ,  Meiko Naruse ,  Shin-Ichi Ayabe ,  Kanki Komiyama ,  Junko Takashima
Affiliations
  • 1. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda-ku, Tokyo 101-0062, Japan. [email protected]
PMID: 15043435 DOI: 10.1021/np030379d
Abstract

Four new triterpenoids with various skeletons, maytefolins A-C (1-3) and uvaol-3-caffeate (4), were isolated from the leaves of a Brazilian medicinal plant, Maytenus ilicifolia, together with five known triterpenoids. Of these triterpenoids only erythrodiol exhibited significant cytotoxicity against KB/S, KB/VJ300, and KU 19-20 cells.