ISLR - immunoglobulin superfamily containing leucine rich repeat Gene

Also Known as Meflin; HsT17563

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3671

About ISLR

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,173,710-74,176,871 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 228 orthologues and 3 paralogues. Broad expression in endometrium (RPKM 88.5), ovary (RPKM 76.4) and 22 other tissues.

Summary

Predicted to be involved in cell adhesion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

ISLR Products (2)

mRNA Protein Name
NM_005545.4 NP_005536.1 immunoglobulin superfamily containing leucine-rich repeat protein precursor
NM_201526.2 NP_958934.1 immunoglobulin superfamily containing leucine-rich repeat protein precursor

ISLR Protein Structure

LRR_8

LRR_8: Leucine rich repeat (51 - 110)

LRR_8

LRR_8: Leucine rich repeat (123 - 181)

I-set

I-set: Immunoglobulin I-set domain (245 - 342)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 428 a.a.
Protein Preferred Names Protein Names

immunoglobulin superfamily containing leucine-rich repeat protein

  • mesenchymal stromal cell- and fibroblast-expressing Linx paralogue

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06933 ISLR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06934 ISLR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16267 Islr Mouse Pre-designed siRNA Set A / Unkown
HY-RS16268 Islr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ISLR MGD MGI:1349645
Macaca mulatta ISLR VGNC VGNC:73771
Bos taurus ISLR VGNC VGNC:30298
Canis familiaris ISLR VGNC VGNC:42110
Rattus norvegicus ISLR RGD RGD:1596359
Felis catus ISLR VGNC VGNC:67835
Others ISLR NCBI