666-15 (Standard)
666-15 (Standard) is the analytical standard of 666-15 (HY-101120). This product is intended for research and analytical applications. 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. 666-15 suppresses tumor growth in a breast cancer xenograft model.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98%
- No. CAS: 1433286-70-4
- Fòrmula: C33H31Cl2N3O5
- Peso molecular:620.52
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
-
HY-101120
666-15CREB Inhibitor -
HY-103299
KG-501CREB Inhibitor -
HY-15743
BirabresibBRD2/3/4 Inhibitor -
HY-13235
I-BET151BRD2/3/4 Inhibitor -
HY-78695
JQ-1 carboxylic acidBET Bromodomain Inhibitor -
HY-103299R
KG-501 (Standard)Reference Standard -
HY-100351
BI-7273BRD9 Inhibitor -
HY-13032
MolibresibBET Inhibitor -
HY-16652
ApabetaloneBET Inhibitor -
HY-100015
MivebresibBET Inhibitor -
HY-18975
I-BRD9Chemical Probe -
HY-112090
ABBV-744BD2 Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
No. CAS 1433286-70-4
-
Peso molecular 620.52
-
Fòrmula C33H31Cl2N3O5
-
SMILES
O=C(NC1=CC=C(Cl)C=C1O)C2=CC3=CC=CC=C3C=C2OCCNC(C4=C(OCCCN)C=C(C=CC=C5)C5=C4)=O.Cl
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Xie F, et al. Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity. J Med Chem. 2015 Jun 25;58(12):5075-87. [Content Brief]
[2]. Qin Y, et al. Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Sci Adv. 2020 Feb 19;6(8):eaaw9960. [Content Brief]
[3]. Zhang B, et al. C1q-TNF-related protein-3 attenuates pressure overload-induced cardiac hypertrophy by suppressing the p38/CREB pathway and p38-induced ER stress. Cell Death Dis. 2019 Jul 8;10(7):520. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
666-15 (Standard) Related Classifications
HY-101120R Related Classifications
Powered by Bioz