Ap5dT
Ap5dT is a cytosolic thymidine kinase and mitochondrial enzyme inhibitor with Kis of 0.12 μM and 0.50 μM, respectively. Ap5dT can be used for the study of acute myelocytic leukemia.
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- No. CAS: 103137-88-8
- Fòrmula: C20H30N7O23P5
- Peso molecular:891.35
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
14 μM
Compound: Ap5T
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Concentration required to reduce Ribonucleotide reductase rate by 50% in L1210 cells
Concentration required to reduce Ribonucleotide reductase rate by 50% in L1210 cells
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[PMID: 2838631] |
| L1210 | IC50 |
2.5 μM
Compound: Ap5T
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Concentration required to reduce thymidine kinase rate by 50% in L1210 cells
Concentration required to reduce thymidine kinase rate by 50% in L1210 cells
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[PMID: 2838631] |
Chemical Information
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No. CAS 103137-88-8
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Peso molecular 891.35
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Fòrmula C20H30N7O23P5
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(OP(OP(OC[C@@H](O2)[C@@H](O)C[C@@H]2N3C(NC(C(C)=C3)=O)=O)(O)=O)(O)=O)(O)=O)(O)=O)(O)=O)O[C@H]1N4C5=NC=NC(N)=C5N=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ap5dT Related Classifications
HY-177023 Related Classifications
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